Matches in SemOpenAlex for { <https://semopenalex.org/work/W2996005943> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2996005943 abstract "Abstract This study examined randomized controlled trial data for blonanserin and risperidone in Chinese schizophrenia patients ( N = 264). Data related to historical changes in the Positive and Negative Syndrome Scale (PANSS) were used to successfully construct a longitudinal E max model. Results: (a) The efficacy of the two drugs was similar after week 8, showing a small difference in PANSS reduction. (b) Using the model, we predicted that each 5‐point increase in the baseline FPOS (positive score in PANSS five‐factor subscales) leads to a decrease in the PANSS total scores at week 8 for 2 points in patients administered blonanserin. (c) The effect of blonanserin on prolactin (PRL) elevation was less. The model was used to predict that prolactin elevations in patients administered risperidone were 2.41‐fold of those in patients administered blonanserin. (d) Model quantitation showed that gender is a risk factor for prolactin elevation. Prolactin elevations in female patients were 2.95‐fold of the value in male patients administered the same drug. The model demonstrated Blonanserin has similar antischizophrenic efficacy and less serum prolactin rising compared to risperidone in Chinese patients." @default.
- W2996005943 created "2019-12-26" @default.
- W2996005943 creator A5022187718 @default.
- W2996005943 creator A5037610460 @default.
- W2996005943 creator A5039360390 @default.
- W2996005943 creator A5046624620 @default.
- W2996005943 creator A5064795666 @default.
- W2996005943 creator A5073578726 @default.
- W2996005943 date "2019-12-14" @default.
- W2996005943 modified "2023-10-16" @default.
- W2996005943 title "Model‐based analysis of therapeutic efficacy of blonanserin and risperidone in schizophrenia patients and effects on prolactin: A randomized double‐blind study" @default.
- W2996005943 cites W1555920164 @default.
- W2996005943 cites W1963402089 @default.
- W2996005943 cites W1979700184 @default.
- W2996005943 cites W1992457778 @default.
- W2996005943 cites W2033372335 @default.
- W2996005943 cites W2034006349 @default.
- W2996005943 cites W2042553471 @default.
- W2996005943 cites W2062327263 @default.
- W2996005943 cites W2066786982 @default.
- W2996005943 cites W2083983434 @default.
- W2996005943 cites W2108450329 @default.
- W2996005943 cites W2131838388 @default.
- W2996005943 cites W2150382103 @default.
- W2996005943 cites W2166604754 @default.
- W2996005943 doi "https://doi.org/10.1002/hup.2717" @default.
- W2996005943 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31837240" @default.
- W2996005943 hasPublicationYear "2019" @default.
- W2996005943 type Work @default.
- W2996005943 sameAs 2996005943 @default.
- W2996005943 citedByCount "0" @default.
- W2996005943 crossrefType "journal-article" @default.
- W2996005943 hasAuthorship W2996005943A5022187718 @default.
- W2996005943 hasAuthorship W2996005943A5037610460 @default.
- W2996005943 hasAuthorship W2996005943A5039360390 @default.
- W2996005943 hasAuthorship W2996005943A5046624620 @default.
- W2996005943 hasAuthorship W2996005943A5064795666 @default.
- W2996005943 hasAuthorship W2996005943A5073578726 @default.
- W2996005943 hasConcept C118552586 @default.
- W2996005943 hasConcept C126322002 @default.
- W2996005943 hasConcept C134018914 @default.
- W2996005943 hasConcept C15744967 @default.
- W2996005943 hasConcept C168563851 @default.
- W2996005943 hasConcept C2776412080 @default.
- W2996005943 hasConcept C2779064019 @default.
- W2996005943 hasConcept C2779727114 @default.
- W2996005943 hasConcept C2780057945 @default.
- W2996005943 hasConcept C2780135775 @default.
- W2996005943 hasConcept C71315377 @default.
- W2996005943 hasConcept C71924100 @default.
- W2996005943 hasConceptScore W2996005943C118552586 @default.
- W2996005943 hasConceptScore W2996005943C126322002 @default.
- W2996005943 hasConceptScore W2996005943C134018914 @default.
- W2996005943 hasConceptScore W2996005943C15744967 @default.
- W2996005943 hasConceptScore W2996005943C168563851 @default.
- W2996005943 hasConceptScore W2996005943C2776412080 @default.
- W2996005943 hasConceptScore W2996005943C2779064019 @default.
- W2996005943 hasConceptScore W2996005943C2779727114 @default.
- W2996005943 hasConceptScore W2996005943C2780057945 @default.
- W2996005943 hasConceptScore W2996005943C2780135775 @default.
- W2996005943 hasConceptScore W2996005943C71315377 @default.
- W2996005943 hasConceptScore W2996005943C71924100 @default.
- W2996005943 hasIssue "1" @default.
- W2996005943 hasLocation W29960059431 @default.
- W2996005943 hasOpenAccess W2996005943 @default.
- W2996005943 hasPrimaryLocation W29960059431 @default.
- W2996005943 hasRelatedWork W1966625438 @default.
- W2996005943 hasRelatedWork W1970823640 @default.
- W2996005943 hasRelatedWork W1989173141 @default.
- W2996005943 hasRelatedWork W1990399071 @default.
- W2996005943 hasRelatedWork W2035021492 @default.
- W2996005943 hasRelatedWork W2060076556 @default.
- W2996005943 hasRelatedWork W2093676636 @default.
- W2996005943 hasRelatedWork W2120307014 @default.
- W2996005943 hasRelatedWork W2121446313 @default.
- W2996005943 hasRelatedWork W2748952813 @default.
- W2996005943 hasVolume "35" @default.
- W2996005943 isParatext "false" @default.
- W2996005943 isRetracted "false" @default.
- W2996005943 magId "2996005943" @default.
- W2996005943 workType "article" @default.