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- W2996152041 abstract "Microincision vitrectomy surgery (MIVS) and small-gauge instrumentation have improved vitrectomy procedures and increased their application in a range of vitreoretinal conditions. The objective of this systematic literature review was to identify publications reporting the efficacy and safety of MIVS tools in vitreoretinal diseases in clinical and real-world settings. Search strategies using key terms were conducted in Embase®, PubMed®, and Cochrane databases, supplemented with grey literature searches. Citations were reviewed by two independent researchers. Comparative clinical trials and observational studies were included. Outcomes of interest included visual acuity, surgical success, and complications. Overall, 1,323 publications were retrieved and systematically screened for eligibility. Twenty comparative publications were eligible for analysis. The majority (n=13) of included publications were observational studies. Comparative evidence in included publications was related to probe gauge and cannulas (n=12), surgical platform (n=6), and method (n=2). Post-operative IOP was reported in 14 studies, with four publications reporting significant improvement in IOP compared to baseline, regardless of probe gauge, and two publications reporting significant differences related to the surgical platform. Procedure time was reported in 13 publications, for various procedures, ranging from 6 to 57 minutes comparing 20-, 23-, 25-, and 27-gauge instruments. Post-operative BCVA ranged from -0.1 to 1.8 logMAR, with significant improvement from baseline reported in five publications, regardless of gauge. Most commonly reported post-operative complications included hypotony (n=9), ocular hypertension (n=8), vitreous haemorrhage (n=8), and retinal detachment (n=7). There are numerous studies evaluating the use of various MIVS tools in vitreoretinal surgery, however, there is also a high degree of heterogeneity in study design, populations, time of assessment, and surgical tools across studies. The differences in population, vitreoretinal pathology, and time of assessment results in difficulties comparing outcomes across trials. Consistency in the measuring and reporting of outcomes is required to reliably make comparisons across studies." @default.
- W2996152041 created "2019-12-26" @default.
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- W2996152041 date "2019-11-01" @default.
- W2996152041 modified "2023-10-18" @default.
- W2996152041 title "PMU1 A SYSTEMATIC LITERATURE REVIEW OF THE EFFICACY AND SAFETY OF MICROINCISION VITRECTOMY SURGERY TOOLS IN VITREORETINAL DISEASES" @default.
- W2996152041 doi "https://doi.org/10.1016/j.jval.2019.09.1620" @default.
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