FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2996174722> ?p ?o ?g. }

• W2996174722 abstract "Background Type 2 diabetes mellitus (T2DM) is a chronic disorder of which stress is a major contributor. Under stressful condition, body synthesizes a family of molecular chaperone called Heat-shock proteins (HSPs). Current study assessed the frequency and association of HSP70-hom + 2,437 T/C polymorphism with T2DM risk among Bangladeshis. Methods This polymorphism was selected through bioinformatics analyses and identified by PCR-RFLP method. Results Bioinformatics analysis identified this SNP as missense mutation which could destabilize the final HSP product. Heterozygous mutant (CT) genotype was significantly associated with T2DM incidence among the studied populations (p = .015). Further analysis revealed a strong association with female patients (p = .002), while the male group showed no association (p = .958). Moreover, the C allele was significantly associated among all diabetic patients (p = .016) and particularly in the female patient group (p = .001). However, under stressful condition, males with CT genotype were at high risk for T2DM incidence whereas, females with CT genotype showed no significant association. Conclusions HSP70-hom + 2,437 T/C polymorphism was found to be significantly associated with T2DM incidence in the Bangladeshi population in both stress-dependent and independent manners." @default.
• W2996174722 created "2019-12-26" @default.
• W2996174722 creator A5015010448 @default.
• W2996174722 creator A5016728233 @default.
• W2996174722 creator A5019868672 @default.
• W2996174722 creator A5035678510 @default.
• W2996174722 creator A5053331183 @default.
• W2996174722 creator A5056448400 @default.
• W2996174722 creator A5059885577 @default.
• W2996174722 creator A5061029754 @default.
• W2996174722 creator A5066441206 @default.
• W2996174722 creator A5082834122 @default.
• W2996174722 creator A5087833981 @default.
• W2996174722 date "2019-12-09" @default.
• W2996174722 modified "2023-10-01" @default.
• W2996174722 title "Association of polymorphism in heat shock protein 70 genes with type 2 diabetes in Bangladeshi population" @default.
• W2996174722 cites W1975543533 @default.
• W2996174722 cites W1986191025 @default.
• W2996174722 cites W1987403914 @default.
• W2996174722 cites W1995107960 @default.
• W2996174722 cites W1996098886 @default.
• W2996174722 cites W2003132592 @default.
• W2996174722 cites W2030448302 @default.
• W2996174722 cites W2047578613 @default.
• W2996174722 cites W2055635286 @default.
• W2996174722 cites W2056973638 @default.
• W2996174722 cites W2059661792 @default.
• W2996174722 cites W2062769159 @default.
• W2996174722 cites W2063214697 @default.
• W2996174722 cites W2066142272 @default.
• W2996174722 cites W2071486470 @default.
• W2996174722 cites W2073031842 @default.
• W2996174722 cites W2082469350 @default.
• W2996174722 cites W2082667898 @default.
• W2996174722 cites W2083031722 @default.
• W2996174722 cites W2083501599 @default.
• W2996174722 cites W2088580357 @default.
• W2996174722 cites W2102694004 @default.
• W2996174722 cites W2116863942 @default.
• W2996174722 cites W2122732537 @default.
• W2996174722 cites W2123544210 @default.
• W2996174722 cites W2160731903 @default.
• W2996174722 cites W2160902434 @default.
• W2996174722 cites W2165113979 @default.
• W2996174722 cites W2169902960 @default.
• W2996174722 cites W2173379110 @default.
• W2996174722 cites W2205674728 @default.
• W2996174722 cites W2329947180 @default.
• W2996174722 cites W2592616394 @default.
• W2996174722 cites W2883021388 @default.
• W2996174722 doi "https://doi.org/10.1002/mgg3.1073" @default.
• W2996174722 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7005638" @default.
• W2996174722 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31816668" @default.
• W2996174722 hasPublicationYear "2019" @default.
• W2996174722 type Work @default.
• W2996174722 sameAs 2996174722 @default.
• W2996174722 citedByCount "6" @default.
• W2996174722 countsByYear W29961747222021 @default.
• W2996174722 countsByYear W29961747222022 @default.
• W2996174722 countsByYear W29961747222023 @default.
• W2996174722 crossrefType "journal-article" @default.
• W2996174722 hasAuthorship W2996174722A5015010448 @default.
• W2996174722 hasAuthorship W2996174722A5016728233 @default.
• W2996174722 hasAuthorship W2996174722A5019868672 @default.
• W2996174722 hasAuthorship W2996174722A5035678510 @default.
• W2996174722 hasAuthorship W2996174722A5053331183 @default.
• W2996174722 hasAuthorship W2996174722A5056448400 @default.
• W2996174722 hasAuthorship W2996174722A5059885577 @default.
• W2996174722 hasAuthorship W2996174722A5061029754 @default.
• W2996174722 hasAuthorship W2996174722A5066441206 @default.
• W2996174722 hasAuthorship W2996174722A5082834122 @default.
• W2996174722 hasAuthorship W2996174722A5087833981 @default.
• W2996174722 hasBestOaLocation W29961747223 @default.
• W2996174722 hasConcept C104317684 @default.
• W2996174722 hasConcept C120665830 @default.
• W2996174722 hasConcept C121332964 @default.
• W2996174722 hasConcept C126322002 @default.
• W2996174722 hasConcept C134018914 @default.
• W2996174722 hasConcept C135763542 @default.
• W2996174722 hasConcept C139275648 @default.
• W2996174722 hasConcept C149737253 @default.
• W2996174722 hasConcept C153209595 @default.
• W2996174722 hasConcept C180754005 @default.
• W2996174722 hasConcept C205260736 @default.
• W2996174722 hasConcept C2777180221 @default.
• W2996174722 hasConcept C2908647359 @default.
• W2996174722 hasConcept C2910068830 @default.
• W2996174722 hasConcept C501734568 @default.
• W2996174722 hasConcept C54355233 @default.
• W2996174722 hasConcept C555293320 @default.
• W2996174722 hasConcept C61511704 @default.
• W2996174722 hasConcept C71924100 @default.
• W2996174722 hasConcept C75563809 @default.
• W2996174722 hasConcept C86803240 @default.
• W2996174722 hasConcept C99454951 @default.
• W2996174722 hasConceptScore W2996174722C104317684 @default.
• W2996174722 hasConceptScore W2996174722C120665830 @default.
• W2996174722 hasConceptScore W2996174722C121332964 @default.
• W2996174722 hasConceptScore W2996174722C126322002 @default.
• W2996174722 hasConceptScore W2996174722C134018914 @default.

• next