Matches in SemOpenAlex for { <https://semopenalex.org/work/W2996314493> ?p ?o ?g. }
- W2996314493 endingPage "14" @default.
- W2996314493 startingPage "1" @default.
- W2996314493 abstract "The pulpotomy with pulp capping is aimed at retaining vital pulp with reparative dentin formation. Vascular endothelial growth factor (VEGF) plays a crucial role in dentin regeneration; however, its constant administrations in the human body is still problematic. Chitosan was widely studied as an effective carrier to deliver bioactive molecules in regenerative medicine. In this study, we conducted a chitosan/ β -glycerophosphate (CS/ β -GP) hydrogel as a VEGF-sustained release system and explored its effects on dental pulp stem cells (DPSCs). CS/ β -GP hydrogel was manufactured using a sol-gel method. SEM assay showed the spongy and porous microstructure of the lyophilized hydrogels. DPSCs cultured in the CS/ β -GP hydrogel kept adhesion and vitality. CCK-8 assay tested the promoted proliferation activity of DPSCs on the hydrogel. Besides, the added VEGF protein could continually release from VEGF/CS/ β -GP hydrogel. The VEGF/CS/ β -GP hydrogel could promote the odontogenic differentiation of DPSCs better than VEGF treatment without hydrogel. Our results suggested that CS/ β -GP hydrogel could continually release VEGF and contribute to odontogenic differentiation of DPSCs, thus may become a potential carrier of bioactive molecules in pulp capping therapy." @default.
- W2996314493 created "2019-12-26" @default.
- W2996314493 creator A5008329236 @default.
- W2996314493 creator A5011277470 @default.
- W2996314493 creator A5011562566 @default.
- W2996314493 creator A5025594263 @default.
- W2996314493 creator A5032152807 @default.
- W2996314493 creator A5034619275 @default.
- W2996314493 creator A5040284332 @default.
- W2996314493 creator A5050458271 @default.
- W2996314493 creator A5062765034 @default.
- W2996314493 creator A5089943316 @default.
- W2996314493 date "2019-12-19" @default.
- W2996314493 modified "2023-10-16" @default.
- W2996314493 title "Evaluation of Chitosan Hydrogel for Sustained Delivery of VEGF for Odontogenic Differentiation of Dental Pulp Stem Cells" @default.
- W2996314493 cites W1848208109 @default.
- W2996314493 cites W1877301297 @default.
- W2996314493 cites W1972246900 @default.
- W2996314493 cites W1980875076 @default.
- W2996314493 cites W1993815068 @default.
- W2996314493 cites W2000602368 @default.
- W2996314493 cites W2017027107 @default.
- W2996314493 cites W2033524865 @default.
- W2996314493 cites W2034094119 @default.
- W2996314493 cites W2035884873 @default.
- W2996314493 cites W2037613017 @default.
- W2996314493 cites W2043209618 @default.
- W2996314493 cites W2044168851 @default.
- W2996314493 cites W2051862078 @default.
- W2996314493 cites W2059338762 @default.
- W2996314493 cites W2065307591 @default.
- W2996314493 cites W2071167287 @default.
- W2996314493 cites W2076276686 @default.
- W2996314493 cites W2078778324 @default.
- W2996314493 cites W2081067332 @default.
- W2996314493 cites W2081994183 @default.
- W2996314493 cites W2086775219 @default.
- W2996314493 cites W2091729240 @default.
- W2996314493 cites W2097619822 @default.
- W2996314493 cites W2106035984 @default.
- W2996314493 cites W2130516299 @default.
- W2996314493 cites W2142634248 @default.
- W2996314493 cites W2148821877 @default.
- W2996314493 cites W2164321850 @default.
- W2996314493 cites W2164906525 @default.
- W2996314493 cites W2170386940 @default.
- W2996314493 cites W2174949899 @default.
- W2996314493 cites W2295778047 @default.
- W2996314493 cites W2339966245 @default.
- W2996314493 cites W2465325180 @default.
- W2996314493 cites W2478348179 @default.
- W2996314493 cites W2484055425 @default.
- W2996314493 cites W2526253255 @default.
- W2996314493 cites W2560816184 @default.
- W2996314493 cites W2567622903 @default.
- W2996314493 cites W2595369186 @default.
- W2996314493 cites W2599007678 @default.
- W2996314493 cites W2608687403 @default.
- W2996314493 cites W2610371574 @default.
- W2996314493 cites W2613391079 @default.
- W2996314493 cites W2620778436 @default.
- W2996314493 cites W2740610303 @default.
- W2996314493 cites W2789733978 @default.
- W2996314493 cites W2892483085 @default.
- W2996314493 cites W2893058683 @default.
- W2996314493 cites W2894997524 @default.
- W2996314493 cites W4292763008 @default.
- W2996314493 cites W93742189 @default.
- W2996314493 doi "https://doi.org/10.1155/2019/1515040" @default.
- W2996314493 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6942904" @default.
- W2996314493 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31949434" @default.
- W2996314493 hasPublicationYear "2019" @default.
- W2996314493 type Work @default.
- W2996314493 sameAs 2996314493 @default.
- W2996314493 citedByCount "39" @default.
- W2996314493 countsByYear W29963144932020 @default.
- W2996314493 countsByYear W29963144932021 @default.
- W2996314493 countsByYear W29963144932022 @default.
- W2996314493 countsByYear W29963144932023 @default.
- W2996314493 crossrefType "journal-article" @default.
- W2996314493 hasAuthorship W2996314493A5008329236 @default.
- W2996314493 hasAuthorship W2996314493A5011277470 @default.
- W2996314493 hasAuthorship W2996314493A5011562566 @default.
- W2996314493 hasAuthorship W2996314493A5025594263 @default.
- W2996314493 hasAuthorship W2996314493A5032152807 @default.
- W2996314493 hasAuthorship W2996314493A5034619275 @default.
- W2996314493 hasAuthorship W2996314493A5040284332 @default.
- W2996314493 hasAuthorship W2996314493A5050458271 @default.
- W2996314493 hasAuthorship W2996314493A5062765034 @default.
- W2996314493 hasAuthorship W2996314493A5089943316 @default.
- W2996314493 hasBestOaLocation W29963144931 @default.
- W2996314493 hasConcept C108586683 @default.
- W2996314493 hasConcept C167734588 @default.
- W2996314493 hasConcept C171056886 @default.
- W2996314493 hasConcept C185592680 @default.
- W2996314493 hasConcept C188027245 @default.
- W2996314493 hasConcept C188442228 @default.
- W2996314493 hasConcept C199343813 @default.