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- W2996354388 abstract "Due to the inconvenience of application, risk of extra damage to fragile soft tissues, and the high incidence of late-stage complications, significant research endeavors have been focused on developing safe and effective bioadhesives to replace or assist the traditional suture techniques for wound closure. Here, we describe a fast and high strength bioadhesive based on polysaccharides and peptide dendrimers (OCMC/G3KP) with inherent hemostatic ability and antibacterial properties. Compared with the commercial bioadhesive Coseal, the OCMC/G3KP hydrogel shows a remarkable 5-fold increase in adhesion strength. The in vivo studies further confirm the superior wound healing performance of the OCMC/G3KP hydrogel in contrast with Coseal and conventional sutures. The OCMC/G3KP hydrogels are efficient and biocompatible bioadhesives with precise controllability that could be flexibly modulated to meet diverse clinical demands." @default.
- W2996354388 created "2019-12-26" @default.
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- W2996354388 date "2019-12-20" @default.
- W2996354388 modified "2023-10-14" @default.
- W2996354388 title "Fast and High Strength Soft Tissue Bioadhesives Based on a Peptide Dendrimer with Antimicrobial Properties and Hemostatic Ability" @default.
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- W2996354388 doi "https://doi.org/10.1021/acsami.9b18720" @default.
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