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• W2996357020 abstract "Ionising radiation (IR) is known to induce a wide variety of lesions in DNA. In this review, we compared three different techniques that examined the DNA sequence preference of IR-induced DNA damage at nucleotide resolution. These three techniques were: the linear amplification/polymerase stop assay, the end-labelling procedure, and Illumina next-generation genome-wide sequencing. The DNA sequence preference of IR-induced DNA damage was compared in purified DNA sequences including human genomic DNA. It was found that the DNA sequence preference of IR-induced DNA damage identified by the end-labelling procedure (that mainly detected single-strand breaks) and Illumina next-generation genome-wide sequencing (that mainly detected double-strand breaks) was at C nucleotides, while the linear amplification/polymerase stop assay (that mainly detected base damage) was at G nucleotides. A consensus sequence at the IR-induced DNA damage was found to be 5′-AGGC*C for the end-labelling technique, 5′-GGC*MH (where * is the cleavage site, M is A or C, H is any nucleotide except G) for the genome-wide technique, and 5′-GG* for the linear amplification/polymerase stop procedure. These three different approaches are important because they provide a deeper insight into the mechanism of action of IR-induced DNA damage." @default.
• W2996357020 created "2019-12-26" @default.
• W2996357020 creator A5000734972 @default.
• W2996357020 creator A5034454568 @default.
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• W2996357020 date "2019-12-20" @default.
• W2996357020 modified "2023-09-27" @default.
• W2996357020 title "Comparison of Different Methods to Determine the DNA Sequence Preference of Ionising Radiation-Induced DNA Damage" @default.
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• W2996357020 cites W1500447870 @default.
• W2996357020 cites W1548528866 @default.
• W2996357020 cites W1558631717 @default.
• W2996357020 cites W1568134298 @default.
• W2996357020 cites W1602417853 @default.
• W2996357020 cites W1845715719 @default.
• W2996357020 cites W1967655663 @default.
• W2996357020 cites W1968938543 @default.
• W2996357020 cites W1972972944 @default.
• W2996357020 cites W1977128472 @default.
• W2996357020 cites W1980815569 @default.
• W2996357020 cites W1983598709 @default.
• W2996357020 cites W1983626749 @default.
• W2996357020 cites W1984266465 @default.
• W2996357020 cites W1990491149 @default.
• W2996357020 cites W1990605458 @default.
• W2996357020 cites W1991164430 @default.
• W2996357020 cites W1991682155 @default.
• W2996357020 cites W1999205993 @default.
• W2996357020 cites W2001382956 @default.
• W2996357020 cites W2006780366 @default.
• W2996357020 cites W2007369689 @default.
• W2996357020 cites W2015838301 @default.
• W2996357020 cites W2019963243 @default.
• W2996357020 cites W2020870451 @default.
• W2996357020 cites W2025548737 @default.
• W2996357020 cites W2026084209 @default.
• W2996357020 cites W2028025897 @default.
• W2996357020 cites W2032732332 @default.
• W2996357020 cites W2034242326 @default.
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• W2996357020 cites W2037900060 @default.
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• W2996357020 cites W2040948271 @default.
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• W2996357020 cites W2167894711 @default.
• W2996357020 cites W2168044784 @default.
• W2996357020 cites W2172899499 @default.
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• W2996357020 cites W2207624647 @default.
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• W2996357020 doi "https://doi.org/10.3390/genes11010008" @default.
• W2996357020 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7016695" @default.
• W2996357020 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31861886" @default.
• W2996357020 hasPublicationYear "2019" @default.
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