FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2996477462> ?p ?o ?g. }

• W2996477462 endingPage "1413" @default.
• W2996477462 startingPage "1400" @default.
• W2996477462 abstract "This study aimed at isolating endophytic fungi from Citrus limon (L.) possessing antioxidative and genoprotective potential.Endophytic fungi were screened for antioxidant activity using 2,2-diphenyl,1-picryl hydrazyl radical scavenging assay and maximum activity (79·70%) was exhibited by culture MP1 identified to be Penicillium oxalicum on the basis of morphological and molecular characteristics. The ethyl acetate extract of MP1 was subjected to silica column chromatography followed by LH 20 column chromatography for purification of active metabolites. The partially purified active fraction of P. oxalicum MP1 possessed good antioxidant activity as detected using various assays. It also exhibited a strong DNA damage protection potential on pUC19 plasmid DNA treated with Fenton reagent. On exposure to active fraction of MP1 significant reduction (P < 0·05) in nuclear deformities (like nuclear buds, micronuclei, nuclear ridges and binucleated cells) was observed in human lymphocytes pretreated with a toxic concentration of H2 O2 . In vivo genoprotectivity studies were conducted in fresh water fish Channa punctatus pretreated with a damaging compound 4-nonyl phenol. The active fraction of P. oxalicum MP1 caused a reduction of 94·7 and 66·60% in micronuclei and aberrant cell formation, respectively. A significant reduction (P < 0·05) in tail length and tail DNA parameters was also observed in comet assay.The endophytic P. oxalicum isolated in this study has the potential to produce metabolites possessing antioxidant and genoprotective activities.The isolated culture can be exploited in the field of therapeutics by virtue of its in vitro and in vivo genoprotective potential." @default.
• W2996477462 created "2019-12-26" @default.
• W2996477462 creator A5015303455 @default.
• W2996477462 creator A5020440814 @default.
• W2996477462 creator A5038145601 @default.
• W2996477462 creator A5040074339 @default.
• W2996477462 creator A5065228033 @default.
• W2996477462 creator A5091826270 @default.
• W2996477462 date "2020-05-01" @default.
• W2996477462 modified "2023-10-13" @default.
• W2996477462 title "An endophytic <i>Penicillium oxalicum</i> isolated from <i>Citrus limon</i> possesses antioxidant and genoprotective potential" @default.
• W2996477462 cites W1497717446 @default.
• W2996477462 cites W1965789311 @default.
• W2996477462 cites W1971270823 @default.
• W2996477462 cites W1972986614 @default.
• W2996477462 cites W1976642063 @default.
• W2996477462 cites W1977920395 @default.
• W2996477462 cites W1983310681 @default.
• W2996477462 cites W1984043156 @default.
• W2996477462 cites W1985031521 @default.
• W2996477462 cites W1999528132 @default.
• W2996477462 cites W2005156172 @default.
• W2996477462 cites W2012991711 @default.
• W2996477462 cites W2027701352 @default.
• W2996477462 cites W2031596649 @default.
• W2996477462 cites W2036052021 @default.
• W2996477462 cites W2046538400 @default.
• W2996477462 cites W2050361501 @default.
• W2996477462 cites W2062977464 @default.
• W2996477462 cites W2064101008 @default.
• W2996477462 cites W2080321076 @default.
• W2996477462 cites W2082748059 @default.
• W2996477462 cites W2087541565 @default.
• W2996477462 cites W2108127101 @default.
• W2996477462 cites W2110237294 @default.
• W2996477462 cites W2123628489 @default.
• W2996477462 cites W2136927468 @default.
• W2996477462 cites W2151841447 @default.
• W2996477462 cites W2165555922 @default.
• W2996477462 cites W2174812022 @default.
• W2996477462 cites W2214192795 @default.
• W2996477462 cites W2221914615 @default.
• W2996477462 cites W2308714110 @default.
• W2996477462 cites W2371460981 @default.
• W2996477462 cites W2528994709 @default.
• W2996477462 cites W2566624203 @default.
• W2996477462 cites W2592854882 @default.
• W2996477462 cites W2751667999 @default.
• W2996477462 cites W2755558750 @default.
• W2996477462 cites W2781896749 @default.
• W2996477462 cites W2791014670 @default.
• W2996477462 cites W2808346138 @default.
• W2996477462 cites W620375347 @default.
• W2996477462 doi "https://doi.org/10.1111/jam.14553" @default.
• W2996477462 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31841255" @default.
• W2996477462 hasPublicationYear "2020" @default.
• W2996477462 type Work @default.
• W2996477462 sameAs 2996477462 @default.
• W2996477462 citedByCount "13" @default.
• W2996477462 countsByYear W29964774622021 @default.
• W2996477462 countsByYear W29964774622022 @default.
• W2996477462 countsByYear W29964774622023 @default.
• W2996477462 crossrefType "journal-article" @default.
• W2996477462 hasAuthorship W2996477462A5015303455 @default.
• W2996477462 hasAuthorship W2996477462A5020440814 @default.
• W2996477462 hasAuthorship W2996477462A5038145601 @default.
• W2996477462 hasAuthorship W2996477462A5040074339 @default.
• W2996477462 hasAuthorship W2996477462A5065228033 @default.
• W2996477462 hasAuthorship W2996477462A5091826270 @default.
• W2996477462 hasConcept C143425029 @default.
• W2996477462 hasConcept C150903083 @default.
• W2996477462 hasConcept C178790620 @default.
• W2996477462 hasConcept C185592680 @default.
• W2996477462 hasConcept C207001950 @default.
• W2996477462 hasConcept C2778004101 @default.
• W2996477462 hasConcept C2779858419 @default.
• W2996477462 hasConcept C2780358455 @default.
• W2996477462 hasConcept C2781401929 @default.
• W2996477462 hasConcept C29730261 @default.
• W2996477462 hasConcept C31903555 @default.
• W2996477462 hasConcept C43617362 @default.
• W2996477462 hasConcept C45080847 @default.
• W2996477462 hasConcept C51724486 @default.
• W2996477462 hasConcept C552990157 @default.
• W2996477462 hasConcept C55493867 @default.
• W2996477462 hasConcept C59822182 @default.
• W2996477462 hasConcept C86803240 @default.
• W2996477462 hasConcept C89638049 @default.
• W2996477462 hasConceptScore W2996477462C143425029 @default.
• W2996477462 hasConceptScore W2996477462C150903083 @default.
• W2996477462 hasConceptScore W2996477462C178790620 @default.
• W2996477462 hasConceptScore W2996477462C185592680 @default.
• W2996477462 hasConceptScore W2996477462C207001950 @default.
• W2996477462 hasConceptScore W2996477462C2778004101 @default.
• W2996477462 hasConceptScore W2996477462C2779858419 @default.
• W2996477462 hasConceptScore W2996477462C2780358455 @default.
• W2996477462 hasConceptScore W2996477462C2781401929 @default.
• W2996477462 hasConceptScore W2996477462C29730261 @default.

• next