FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W299651657> ?p ?o ?g. }

• W299651657 endingPage "794" @default.
• W299651657 startingPage "789" @default.
• W299651657 abstract "Research Article1 April 1984free access Adenovirus 2 early region 1A stimulates expression of both viral and cellular genes. C. Svensson C. Svensson Search for more papers by this author G. Akusjärvi G. Akusjärvi Search for more papers by this author C. Svensson C. Svensson Search for more papers by this author G. Akusjärvi G. Akusjärvi Search for more papers by this author Author Information C. Svensson and G. Akusjärvi The EMBO Journal (1984)3:789-794https://doi.org/10.1002/j.1460-2075.1984.tb01886.x PDFDownload PDF of article text and main figures. ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InMendeleyWechatReddit Figures & Info The ability of products from the adenovirus early region 1A to stimulate viral and cellular gene expression has been studied, using a transient expression assay in HeLa cells. We show that the E1A 13S mRNA encodes a diffusible product which is capable of stimulating transcription of adenovirus genes as well as the rabbit beta-globin gene. The E1A 12S mRNA has no detectable stimulatory effect on either cellular or viral genes. Although being able to stimulate both types of genes, we find that the E1A regulatory protein enhances viral gene expression approximately 10 times more than beta-globin gene expression. We also find that when connected to the cis-acting SV40 enhancer element, the beta-globin gene cannot be further stimulated by the trans-acting E1A product. Finally, we find that transfection of either adenovirus or the beta-globin gene into 293 cells, which constitutively expresses the E1A gene products, leads to an enhanced expression which is 10- to 20-fold higher than obtained by co-transfection of HeLa cells. The 293 cells thus provide a simple assay to demonstrate E1A-mediated transcriptional regulation. Previous ArticleNext Article Volume 3Issue 41 April 1984In this issue RelatedDetailsLoading ..." @default.
• W299651657 created "2016-06-24" @default.
• W299651657 creator A5035558887 @default.
• W299651657 creator A5084125183 @default.
• W299651657 date "1984-04-01" @default.
• W299651657 modified "2023-10-15" @default.
• W299651657 title "Adenovirus 2 early region 1A stimulates expression of both viral and cellular genes." @default.
• W299651657 cites W1532984977 @default.
• W299651657 cites W1554235025 @default.
• W299651657 cites W1584231747 @default.
• W299651657 cites W1801995484 @default.
• W299651657 cites W1911213431 @default.
• W299651657 cites W1926037744 @default.
• W299651657 cites W1933956890 @default.
• W299651657 cites W1967478094 @default.
• W299651657 cites W1968215478 @default.
• W299651657 cites W1973106610 @default.
• W299651657 cites W1979498694 @default.
• W299651657 cites W1987975025 @default.
• W299651657 cites W1998162329 @default.
• W299651657 cites W2000092309 @default.
• W299651657 cites W2010675102 @default.
• W299651657 cites W2013160989 @default.
• W299651657 cites W2013835780 @default.
• W299651657 cites W2014593543 @default.
• W299651657 cites W2024540147 @default.
• W299651657 cites W2032258076 @default.
• W299651657 cites W2032343668 @default.
• W299651657 cites W2044296969 @default.
• W299651657 cites W2046881557 @default.
• W299651657 cites W2058795593 @default.
• W299651657 cites W2067956561 @default.
• W299651657 cites W2069589902 @default.
• W299651657 cites W2073392316 @default.
• W299651657 cites W2074635397 @default.
• W299651657 cites W2092216600 @default.
• W299651657 cites W2116951270 @default.
• W299651657 cites W2117079180 @default.
• W299651657 cites W2120479947 @default.
• W299651657 cites W2126948870 @default.
• W299651657 cites W2137759749 @default.
• W299651657 cites W2139759154 @default.
• W299651657 cites W2158290831 @default.
• W299651657 cites W2160348498 @default.
• W299651657 cites W2163077591 @default.
• W299651657 cites W2306852714 @default.
• W299651657 cites W4234408131 @default.
• W299651657 doi "https://doi.org/10.1002/j.1460-2075.1984.tb01886.x" @default.
• W299651657 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/557428" @default.
• W299651657 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6723627" @default.
• W299651657 hasPublicationYear "1984" @default.
• W299651657 type Work @default.
• W299651657 sameAs 299651657 @default.
• W299651657 citedByCount "147" @default.
• W299651657 countsByYear W2996516572013 @default.
• W299651657 countsByYear W2996516572016 @default.
• W299651657 crossrefType "journal-article" @default.
• W299651657 hasAuthorship W299651657A5035558887 @default.
• W299651657 hasAuthorship W299651657A5084125183 @default.
• W299651657 hasBestOaLocation W2996516571 @default.
• W299651657 hasConcept C104317684 @default.
• W299651657 hasConcept C111936080 @default.
• W299651657 hasConcept C125996951 @default.
• W299651657 hasConcept C138885662 @default.
• W299651657 hasConcept C150194340 @default.
• W299651657 hasConcept C153911025 @default.
• W299651657 hasConcept C179926584 @default.
• W299651657 hasConcept C195286587 @default.
• W299651657 hasConcept C41895202 @default.
• W299651657 hasConcept C54009773 @default.
• W299651657 hasConcept C54355233 @default.
• W299651657 hasConcept C86803240 @default.
• W299651657 hasConceptScore W299651657C104317684 @default.
• W299651657 hasConceptScore W299651657C111936080 @default.
• W299651657 hasConceptScore W299651657C125996951 @default.
• W299651657 hasConceptScore W299651657C138885662 @default.
• W299651657 hasConceptScore W299651657C150194340 @default.
• W299651657 hasConceptScore W299651657C153911025 @default.
• W299651657 hasConceptScore W299651657C179926584 @default.
• W299651657 hasConceptScore W299651657C195286587 @default.
• W299651657 hasConceptScore W299651657C41895202 @default.
• W299651657 hasConceptScore W299651657C54009773 @default.
• W299651657 hasConceptScore W299651657C54355233 @default.
• W299651657 hasConceptScore W299651657C86803240 @default.
• W299651657 hasIssue "4" @default.
• W299651657 hasLocation W2996516571 @default.
• W299651657 hasLocation W2996516572 @default.
• W299651657 hasLocation W2996516573 @default.
• W299651657 hasOpenAccess W299651657 @default.
• W299651657 hasPrimaryLocation W2996516571 @default.
• W299651657 hasRelatedWork W2061914098 @default.
• W299651657 hasRelatedWork W2113330652 @default.
• W299651657 hasRelatedWork W2118646732 @default.
• W299651657 hasRelatedWork W2164437319 @default.
• W299651657 hasRelatedWork W2941374428 @default.
• W299651657 hasRelatedWork W2972483091 @default.
• W299651657 hasRelatedWork W4283022034 @default.
• W299651657 hasRelatedWork W4309683845 @default.

• next