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• W2996751439 abstract "Background Recently, a clinical prediction rule has been proposed to predict the chance of successful endoscopic stenting in benign esophageal anastomotic leakage, perforation and fistula. We aimed to validate this score in a cohort of patients with anastomotic leaks managed with self-expanding metal esophageal stents, by assessing technical and clinical success rates and comparing the agreement between the predicted and the actual clinical success. Methods A multicenter retrospective cohort study including patients submitted to endoscopic stenting due to anastomotic leak was conducted. Variables of the score (leak size, location and C-reactive protein) were collected and the chance of success (≤50, 50-70 and ≥70%) and its accuracy was assessed. Results Fifty-three patients, submitted to esophageal stenting after cancer (n = 47) and bariatric surgery were included. Clinical success was achieved in 62% of patients. The area under the ROC curve to differentiate between successful and failed therapies showed a good discriminative power of the score (AUC 0.705; P 50%, the positive predictive value was 72.5%; for a chance of success ≤50%, the negative predictive value was 69.2%. Conclusions The application of this predictive model in patients with anastomotic leaks proved to be valid in a different cohort from that in which it was derived. Its usefulness in clinical practice may be anticipated, favoring stenting in patients with a chance of success >50%. However, we must be cautious in patients with a lower probability of success and a case-by-case decision should be made." @default.
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• W2996751439 date "2020-04-01" @default.
• W2996751439 modified "2023-09-27" @default.
• W2996751439 title "Clinical score predicting a successful endoscopic approach of esophageal anastomotic leaks: external validation" @default.
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• W2996751439 doi "https://doi.org/10.1097/meg.0000000000001621" @default.
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