FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2996753987> ?p ?o ?g. }

• W2996753987 abstract "Abstract Background Transcorneal electrical stimulation (TES; OkuStim ® ) is a novel therapy method for patients with retinitis pigmentosa (RP). With progression of RP, loss of photoreceptors leads to less oxygen consumption and lower demand in the inner retina. Retinal oximetry (RO) as a non‐invasive method to analyze oxygen saturation in retinal vessels promises to be a useful therapy monitoring tool. The aim of our study was to compare the RO parameters at baseline and following TES. Methods A total of 43 eyes of 22 subjects (11♀ 11♂) suffering from RP were examined. Stimulation was performed for 30 minutes weekly at 200% of the individual phosphene threshold on both eyes. The oxygen saturation was examined at baseline (BL), 1 week and 6 months after TES stimulation with the oxygen saturation tool of the Retinal Vessel Analyser (IMEDOS Systems UG, Germany). The global oxygen saturations, within 1.0–1.5 optic disc diameters from the disc margin, in retinal arterioles (A‐SO 2 ; %) and venules (V‐SO 2 ; %) were estimated and their difference (A‐V SO 2 ; %) was calculated. In addition, we evaluated the diameters in the corresponding arterioles (D‐A; μm) and venules (D‐V; μm). ANOVA‐based linear mixed‐effects models were calculated with SPSS ® . Results Six months after TES the A‐SO 2 showed a tendency to increase (from 96.48 ± 12.27% to 100.15 ± 5.56%, p = 0.09), while the V‐SO 2 showed a slight decrease (from 61.61 ± 12.78% to 59.79 ± 11.15%, p = 0.48). The A‐V SO 2 , which represents the oxygen consumption of the retina, showed a significant increase from 34.87 ± 9.38% at BL to 41.36 ± 9.18% after 6 months (p = 0.02). TES had no influence on the D‐A and D‐V (p > 0.6). Conclusion These data indicate that TES therapy in RP leads to an increased oxygen consumption of the retina. Thus, RO proves to serve as a sensitive monitoring method for TES therapy in RP patients." @default.
• W2996753987 created "2019-12-26" @default.
• W2996753987 creator A5040676815 @default.
• W2996753987 creator A5051488992 @default.
• W2996753987 creator A5059328359 @default.
• W2996753987 creator A5076873497 @default.
• W2996753987 creator A5083741826 @default.
• W2996753987 date "2019-12-01" @default.
• W2996753987 modified "2023-10-17" @default.
• W2996753987 title "Retinal vessel oximetry as a sensitive metabolic monitoring method for transcorneal electrical stimulation in retinitis pigmentosa" @default.
• W2996753987 doi "https://doi.org/10.1111/j.1755-3768.2019.5117" @default.
• W2996753987 hasPublicationYear "2019" @default.
• W2996753987 type Work @default.
• W2996753987 sameAs 2996753987 @default.
• W2996753987 citedByCount "0" @default.
• W2996753987 crossrefType "journal-article" @default.
• W2996753987 hasAuthorship W2996753987A5040676815 @default.
• W2996753987 hasAuthorship W2996753987A5051488992 @default.
• W2996753987 hasAuthorship W2996753987A5059328359 @default.
• W2996753987 hasAuthorship W2996753987A5076873497 @default.
• W2996753987 hasAuthorship W2996753987A5083741826 @default.
• W2996753987 hasBestOaLocation W29967539871 @default.
• W2996753987 hasConcept C118487528 @default.
• W2996753987 hasConcept C120665830 @default.
• W2996753987 hasConcept C121332964 @default.
• W2996753987 hasConcept C126322002 @default.
• W2996753987 hasConcept C178790620 @default.
• W2996753987 hasConcept C185592680 @default.
• W2996753987 hasConcept C24998067 @default.
• W2996753987 hasConcept C2777093970 @default.
• W2996753987 hasConcept C2780827179 @default.
• W2996753987 hasConcept C2781114197 @default.
• W2996753987 hasConcept C540031477 @default.
• W2996753987 hasConcept C71924100 @default.
• W2996753987 hasConcept C76538665 @default.
• W2996753987 hasConceptScore W2996753987C118487528 @default.
• W2996753987 hasConceptScore W2996753987C120665830 @default.
• W2996753987 hasConceptScore W2996753987C121332964 @default.
• W2996753987 hasConceptScore W2996753987C126322002 @default.
• W2996753987 hasConceptScore W2996753987C178790620 @default.
• W2996753987 hasConceptScore W2996753987C185592680 @default.
• W2996753987 hasConceptScore W2996753987C24998067 @default.
• W2996753987 hasConceptScore W2996753987C2777093970 @default.
• W2996753987 hasConceptScore W2996753987C2780827179 @default.
• W2996753987 hasConceptScore W2996753987C2781114197 @default.
• W2996753987 hasConceptScore W2996753987C540031477 @default.
• W2996753987 hasConceptScore W2996753987C71924100 @default.
• W2996753987 hasConceptScore W2996753987C76538665 @default.
• W2996753987 hasIssue "S263" @default.
• W2996753987 hasLocation W29967539871 @default.
• W2996753987 hasOpenAccess W2996753987 @default.
• W2996753987 hasPrimaryLocation W29967539871 @default.
• W2996753987 hasRelatedWork W1977334515 @default.
• W2996753987 hasRelatedWork W2029841208 @default.
• W2996753987 hasRelatedWork W2037746501 @default.
• W2996753987 hasRelatedWork W2041896872 @default.
• W2996753987 hasRelatedWork W2093210804 @default.
• W2996753987 hasRelatedWork W2119498694 @default.
• W2996753987 hasRelatedWork W2402796057 @default.
• W2996753987 hasRelatedWork W2698165631 @default.
• W2996753987 hasRelatedWork W4233329698 @default.
• W2996753987 hasRelatedWork W584015088 @default.
• W2996753987 hasVolume "97" @default.
• W2996753987 isParatext "false" @default.
• W2996753987 isRetracted "false" @default.
• W2996753987 magId "2996753987" @default.
• W2996753987 workType "article" @default.