Matches in SemOpenAlex for { <https://semopenalex.org/work/W2996793926> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2996793926 endingPage "106661" @default.
- W2996793926 startingPage "106661" @default.
- W2996793926 abstract "We aimed to investigate factors contributing to ureteral responses and establish a reliable porcine model for studying ureteral contractility. Isolated ureteral strips from young (6-month old) and older (3-year old) pigs were mounted in organ baths and subjected to phenylephrine, 5-HT, carbachol and histamine. Ureteral strips developed bursts of contractile activity which was measured as area under the curve (AUC) and frequency. Phenylephrine and 5-HT-induced responses of proximal and distal ureters were obtained, in the presence and absence of indomethacin (10 μM) and L-NNA (100 μM), and the influence of an intact mucosa was examined. Phenylephrine and 5-HT-induced contractile responses were greater than those to carbachol in the porcine ureter. In fact, responses to carbachol were only present in ureters from older animals. Ureters suspended longitudinally had increased phenylephrine-induced contractions compared to those suspended circularly (p < .05). A greater amount of tissue strips developed spontaneous contractions from the proximal region compared to distal (83% vs 25%). There was an increase in maximum phenylephrine-induced responses in the distal ureter when compared to the proximal ureter (p < .05). In the presence of indomethacin, only 5-HT-induced contractions in the young animals were depressed (p < .05) while L-NNA did not affect any ureteral responses. The intact mucosa significantly decreased contractile responses to phenylephrine and 5-HT in the porcine ureter. The complexity of ureteral contractions depicting bursts of phasic activity requires AUC assessment. Porcine ureteral contractile properties, such as regional differences, influence of mucosa and lack of response to carbachol, are similar to those reported in the literature for human ureter." @default.
- W2996793926 created "2020-01-10" @default.
- W2996793926 creator A5051125867 @default.
- W2996793926 creator A5078482579 @default.
- W2996793926 creator A5082180881 @default.
- W2996793926 date "2020-03-01" @default.
- W2996793926 modified "2023-10-17" @default.
- W2996793926 title "A porcine model of ureteral contractile activity: Influences of age, tissue orientation, region, urothelium, COX and NO" @default.
- W2996793926 cites W1587189580 @default.
- W2996793926 cites W1875022435 @default.
- W2996793926 cites W1967830829 @default.
- W2996793926 cites W1970717513 @default.
- W2996793926 cites W1977163919 @default.
- W2996793926 cites W1986546321 @default.
- W2996793926 cites W1995882056 @default.
- W2996793926 cites W2005222209 @default.
- W2996793926 cites W2025729682 @default.
- W2996793926 cites W2026750366 @default.
- W2996793926 cites W2040643763 @default.
- W2996793926 cites W2046733578 @default.
- W2996793926 cites W2080669817 @default.
- W2996793926 cites W2084187523 @default.
- W2996793926 cites W2086959637 @default.
- W2996793926 cites W2116369728 @default.
- W2996793926 cites W2152569884 @default.
- W2996793926 cites W2161521033 @default.
- W2996793926 cites W2171512008 @default.
- W2996793926 cites W2558234015 @default.
- W2996793926 cites W2767769986 @default.
- W2996793926 cites W2792097772 @default.
- W2996793926 cites W2799528752 @default.
- W2996793926 cites W2807127152 @default.
- W2996793926 cites W2951263076 @default.
- W2996793926 doi "https://doi.org/10.1016/j.vascn.2019.106661" @default.
- W2996793926 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31881277" @default.
- W2996793926 hasPublicationYear "2020" @default.
- W2996793926 type Work @default.
- W2996793926 sameAs 2996793926 @default.
- W2996793926 citedByCount "4" @default.
- W2996793926 countsByYear W29967939262021 @default.
- W2996793926 countsByYear W29967939262022 @default.
- W2996793926 countsByYear W29967939262023 @default.
- W2996793926 crossrefType "journal-article" @default.
- W2996793926 hasAuthorship W2996793926A5051125867 @default.
- W2996793926 hasAuthorship W2996793926A5078482579 @default.
- W2996793926 hasAuthorship W2996793926A5082180881 @default.
- W2996793926 hasBestOaLocation W29967939262 @default.
- W2996793926 hasConcept C105702510 @default.
- W2996793926 hasConcept C126322002 @default.
- W2996793926 hasConcept C126894567 @default.
- W2996793926 hasConcept C134018914 @default.
- W2996793926 hasConcept C24998067 @default.
- W2996793926 hasConcept C2776664737 @default.
- W2996793926 hasConcept C2777226302 @default.
- W2996793926 hasConcept C2777540882 @default.
- W2996793926 hasConcept C2777952589 @default.
- W2996793926 hasConcept C2778988552 @default.
- W2996793926 hasConcept C2779762690 @default.
- W2996793926 hasConcept C39133596 @default.
- W2996793926 hasConcept C71924100 @default.
- W2996793926 hasConcept C84393581 @default.
- W2996793926 hasConceptScore W2996793926C105702510 @default.
- W2996793926 hasConceptScore W2996793926C126322002 @default.
- W2996793926 hasConceptScore W2996793926C126894567 @default.
- W2996793926 hasConceptScore W2996793926C134018914 @default.
- W2996793926 hasConceptScore W2996793926C24998067 @default.
- W2996793926 hasConceptScore W2996793926C2776664737 @default.
- W2996793926 hasConceptScore W2996793926C2777226302 @default.
- W2996793926 hasConceptScore W2996793926C2777540882 @default.
- W2996793926 hasConceptScore W2996793926C2777952589 @default.
- W2996793926 hasConceptScore W2996793926C2778988552 @default.
- W2996793926 hasConceptScore W2996793926C2779762690 @default.
- W2996793926 hasConceptScore W2996793926C39133596 @default.
- W2996793926 hasConceptScore W2996793926C71924100 @default.
- W2996793926 hasConceptScore W2996793926C84393581 @default.
- W2996793926 hasLocation W29967939261 @default.
- W2996793926 hasLocation W29967939262 @default.
- W2996793926 hasLocation W29967939263 @default.
- W2996793926 hasLocation W29967939264 @default.
- W2996793926 hasOpenAccess W2996793926 @default.
- W2996793926 hasPrimaryLocation W29967939261 @default.
- W2996793926 hasRelatedWork W1901275661 @default.
- W2996793926 hasRelatedWork W1966357256 @default.
- W2996793926 hasRelatedWork W1972099714 @default.
- W2996793926 hasRelatedWork W1986343589 @default.
- W2996793926 hasRelatedWork W2022685867 @default.
- W2996793926 hasRelatedWork W2035801811 @default.
- W2996793926 hasRelatedWork W2040046061 @default.
- W2996793926 hasRelatedWork W2057576900 @default.
- W2996793926 hasRelatedWork W2129759033 @default.
- W2996793926 hasRelatedWork W2996793926 @default.
- W2996793926 hasVolume "102" @default.
- W2996793926 isParatext "false" @default.
- W2996793926 isRetracted "false" @default.
- W2996793926 magId "2996793926" @default.
- W2996793926 workType "article" @default.