Matches in SemOpenAlex for { <https://semopenalex.org/work/W2996816900> ?p ?o ?g. }
- W2996816900 endingPage "119719" @default.
- W2996816900 startingPage "119719" @default.
- W2996816900 abstract "Tissue adhesives are commonly used in surgeries and regenerative engineering for the repair and regeneration of topical and internal wounds on tissues and organs such as skin, heart, blood vessels, and bone. However, achieving rapid crosslinking, strong wet adhesion and cohesion strengths, and minimal cytotoxicity remains a critical roadblock for clinical translation. Herein, in contrast to harsh and cytotoxic oxidants, magnesium oxide (MgO) particles were found to facilitate rapid crosslinking for injectable citrate-based mussel-inspired tissue bioadhesives synthesized by reacting citric acid, PEG-PPG-PEG diol and dopamine (iC-EPE). Our results confirmed the role of MgO particles as both crosslinkers and composite fillers to concurrently enhance bioadhesive cohesion and adhesion. iC-EPE crosslinked by MgO with/without sodium periodate (PI) exhibit enhanced mechanical strengths (1.0 Mpa < tensile strength ≤ 4.5 MPa) compared to that of iC-EPE crosslinked only by PI (~0.75 MPa), high adhesion strength (up to 125 kPa, 8 fold that of fibrin glue (~15 kPa)), tunable degradability (full degradation from <1 week to > 1 month), excellent in vitro and in vivo biocompatibility, encouraging anti-bacterial performance, and favorable wound closure efficacy. Thus, MgO crosslinked bioadhesives possess great potential for a wide range of applications in surgery and regenerative engineering." @default.
- W2996816900 created "2020-01-10" @default.
- W2996816900 creator A5006200671 @default.
- W2996816900 creator A5018254630 @default.
- W2996816900 creator A5018768725 @default.
- W2996816900 creator A5019920329 @default.
- W2996816900 creator A5026519250 @default.
- W2996816900 creator A5026542289 @default.
- W2996816900 creator A5026544444 @default.
- W2996816900 creator A5030667329 @default.
- W2996816900 creator A5038254958 @default.
- W2996816900 creator A5043052947 @default.
- W2996816900 creator A5046951299 @default.
- W2996816900 creator A5050570163 @default.
- W2996816900 creator A5059198932 @default.
- W2996816900 creator A5062761052 @default.
- W2996816900 date "2020-02-01" @default.
- W2996816900 modified "2023-10-14" @default.
- W2996816900 title "Magnesium oxide-crosslinked low-swelling citrate-based mussel-inspired tissue adhesives" @default.
- W2996816900 cites W1570005489 @default.
- W2996816900 cites W1860947124 @default.
- W2996816900 cites W1964207157 @default.
- W2996816900 cites W1965947217 @default.
- W2996816900 cites W1990796341 @default.
- W2996816900 cites W2020215321 @default.
- W2996816900 cites W2022943333 @default.
- W2996816900 cites W2025905012 @default.
- W2996816900 cites W2031750162 @default.
- W2996816900 cites W2032302277 @default.
- W2996816900 cites W2032854903 @default.
- W2996816900 cites W2039618696 @default.
- W2996816900 cites W2046114511 @default.
- W2996816900 cites W2055805379 @default.
- W2996816900 cites W2057320703 @default.
- W2996816900 cites W2065622061 @default.
- W2996816900 cites W2074861758 @default.
- W2996816900 cites W2084141237 @default.
- W2996816900 cites W2085170959 @default.
- W2996816900 cites W2087238801 @default.
- W2996816900 cites W2097154200 @default.
- W2996816900 cites W2098568698 @default.
- W2996816900 cites W2139023389 @default.
- W2996816900 cites W2141182758 @default.
- W2996816900 cites W2150757642 @default.
- W2996816900 cites W2272411923 @default.
- W2996816900 cites W2272418652 @default.
- W2996816900 cites W2297273152 @default.
- W2996816900 cites W2313786985 @default.
- W2996816900 cites W2530160466 @default.
- W2996816900 cites W2574180453 @default.
- W2996816900 cites W2598615946 @default.
- W2996816900 cites W2736956052 @default.
- W2996816900 cites W2740710461 @default.
- W2996816900 cites W2770162756 @default.
- W2996816900 cites W2793513753 @default.
- W2996816900 cites W2810561059 @default.
- W2996816900 cites W2903369963 @default.
- W2996816900 cites W601929666 @default.
- W2996816900 doi "https://doi.org/10.1016/j.biomaterials.2019.119719" @default.
- W2996816900 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31901688" @default.
- W2996816900 hasPublicationYear "2020" @default.
- W2996816900 type Work @default.
- W2996816900 sameAs 2996816900 @default.
- W2996816900 citedByCount "58" @default.
- W2996816900 countsByYear W29968169002020 @default.
- W2996816900 countsByYear W29968169002021 @default.
- W2996816900 countsByYear W29968169002022 @default.
- W2996816900 countsByYear W29968169002023 @default.
- W2996816900 crossrefType "journal-article" @default.
- W2996816900 hasAuthorship W2996816900A5006200671 @default.
- W2996816900 hasAuthorship W2996816900A5018254630 @default.
- W2996816900 hasAuthorship W2996816900A5018768725 @default.
- W2996816900 hasAuthorship W2996816900A5019920329 @default.
- W2996816900 hasAuthorship W2996816900A5026519250 @default.
- W2996816900 hasAuthorship W2996816900A5026542289 @default.
- W2996816900 hasAuthorship W2996816900A5026544444 @default.
- W2996816900 hasAuthorship W2996816900A5030667329 @default.
- W2996816900 hasAuthorship W2996816900A5038254958 @default.
- W2996816900 hasAuthorship W2996816900A5043052947 @default.
- W2996816900 hasAuthorship W2996816900A5046951299 @default.
- W2996816900 hasAuthorship W2996816900A5050570163 @default.
- W2996816900 hasAuthorship W2996816900A5059198932 @default.
- W2996816900 hasAuthorship W2996816900A5062761052 @default.
- W2996816900 hasConcept C112950240 @default.
- W2996816900 hasConcept C136229726 @default.
- W2996816900 hasConcept C13965031 @default.
- W2996816900 hasConcept C159985019 @default.
- W2996816900 hasConcept C171250308 @default.
- W2996816900 hasConcept C185592680 @default.
- W2996816900 hasConcept C191897082 @default.
- W2996816900 hasConcept C192562407 @default.
- W2996816900 hasConcept C2776634624 @default.
- W2996816900 hasConcept C2777230088 @default.
- W2996816900 hasConcept C2778414984 @default.
- W2996816900 hasConcept C2778540859 @default.
- W2996816900 hasConcept C2779227376 @default.
- W2996816900 hasConcept C2781472170 @default.
- W2996816900 hasConcept C2910641076 @default.