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- W2996833837 abstract "Objective: Brain network studies have revealed abnormal topology asymmetry of white matter (WM) in ADHD. Recently, rich club organization was proposed to be a key feature of brain network topology. However, abnormalities in the rich club organization of hemispheric WM networks in ADHD remain unclear. Method: Forty ADHD patients and 51 normal controls participated in this study. Structural networks were reconstructed based on diffusion tensor imaging (DTI) and analyzed with graph theory. Results: The two groups exhibited different patterns of asymmetry in connectivity measures of rich club connections. ADHD patients showed more feeder connections than normal controls. Reduced rightward asymmetry was observed in connectivity measures of local connections involving several peripheral regions of the ADHD patients. In addition, abnormal regional asymmetry scores were associated with ADHD symptoms. Conclusion: The topological changes in rich club organization provide a novel insight into the alteration of WM connections in ADHD." @default.
- W2996833837 created "2020-01-10" @default.
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- W2996833837 date "2019-12-30" @default.
- W2996833837 modified "2023-09-27" @default.
- W2996833837 title "Abnormal Rich Club Organization in Hemispheric White Matter Networks of ADHD" @default.
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- W2996833837 doi "https://doi.org/10.1177/1087054719892887" @default.
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