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- W2996836610 abstract "Background: For most major abdominal operations, routine post-operative venous thromboembolism (VTE) chemoprophylaxis has been proven to be both safe and effective, and is now considered the international standard of care for cancer surgery. Hepatopancreatobiliary (HPB) surgeons have frequently withheld VTE chemoprophylaxis owing to the perceived risk of peri-operative haemorrhage. Methods: From 2012 to 2016, 140 patients were underwent high-level hepato-biliary pancreatic surgeries. For VTE prevention, four thousand international units per day of enoxiaparin were administered for all patients from two days to fourteen days after surgery. We analyzed the rates of postoperative bleeding events and morbidity to evaluate the safety and efficacy of postoperative thromboprophylaxis. Results: 60 patients were underwent hepatectomy. Bleeding event were not admitted in all cases of hepatectomy. 80 patients were underwent pancreatectomy. Pseudoaneurysmal bleeding after pancreatoduodenectomy due to pancreatic fistula were admitted 3 patients and underwent with microcoil embolization. 1 patient, a cerebral hemorrhage was admitted early after operation and cancel administer an enoxiaparin. The case of VTE with symptom was not admitted. Postoperative complication with enoxaparin were not observed. Conclusion: Prevention of VTE in our institution is feasible. Cemical thromboprophylaxis did not increase the risk of hemorrhage and can be safely used even after high-level hepato-biliary pancreatic surgeries." @default.
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- W2996836610 date "2019-01-01" @default.
- W2996836610 modified "2023-10-17" @default.
- W2996836610 title "Evaluation of thromboprophylaxis after highly advanced hepatobiliary-pancreatic surgery" @default.
- W2996836610 doi "https://doi.org/10.1016/j.hpb.2019.10.1012" @default.
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