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- W2997035659 abstract "High-grade gliomas (HGG) are the most frequent primary central nervous system tumors; treatment of HCGs includes surgery and post-operative conformal radiotherapy associated with temozolomide (TMZ or procarbazine/lomustine/vincristine [PCV], specifically in patients with anaplastic oligodendrogliomas or anaplastic oligoastrocytomas). However, recurrence is common. Re-irradiation has been utilized in this setting for years and remains a feasible option, although there is always a concern regarding toxicity. Modern high-precision conformal techniques, including stereotactic radiosurgery (SRS), could improve the therapeutic ratio by delivering high biologically equivalent doses while reducing high-dose radiotherapy (RT) to normal brain tissue. In this paper, we present the results obtained after prolonged follow-up in patients who underwent SRS as a treatment for recurrent high-grade gliomas at San Francisco Hospital in Madrid, Spain." @default.
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- W2997035659 date "2019-12-31" @default.
- W2997035659 modified "2023-10-01" @default.
- W2997035659 title "Stereotactic Radiosurgery for the Treatment of Recurrent High-grade Gliomas: Long-term Follow-up" @default.
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- W2997035659 doi "https://doi.org/10.7759/cureus.6527" @default.
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