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- W2997041868 abstract "Bu çalışmada; 7,12-dimethyl benzanthracene (DMBA) ile indüklenen ratlara Tunceli Dağ Sarımsağı (Allium tuncelianum) ve vitamin E uygulamasının, rat bağırsak dokusundaki lipit peroksidasyon ve antioksidan enzim aktivitelerine etkisinin belirlenmesi amaçlandı. Çalışmada, Wistar albino tipi dişi ratlar kullanıldı. Her grupta 8 adet (n=8) hayvan olmak üzere, 5 grup oluşturuldu. 1.Grup; Kontrol grubu, 2.Grup; 7,12-dimethyl benzanthracene (DMBA) verilen grup, 3.Grup; 7.12-DMBA’ya ilaveten 250 mg/kg/gün Tunceli Dağ Sarımsağı (TDS) verilen grup, 4.Grup; 7.12-DMBA’ya ilaveten 500 mg/kg/gün TDS verilen grup ve 5.Grup; 7.12-DMBA’ya ilaveten 200 mg/kg (haftada iki kez) E vitamini verilen gruptu. 30 günlük deneme sonunda; ratlara ötenazi uygulandı ve bağırsak dokusu çıkarılarak homojenize edildi. Bağırsak doku homojenatındaki lipit peroksidasyon ve antioksidan enzim düzeyi spektrofotometrik yöntemle ölçüldü. Çalışma sonucunda DMBA uygulanan grubun (Grup 2) bağırsak dokusunda: katalaz (CAT), total glutatyon (GSH) ve süperoksit dismutaz (SOD) enzim aktivitesinin kontrol grubuna göre anlamlı olarak azaldığı (P" @default.
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- W2997041868 date "2019-12-25" @default.
- W2997041868 modified "2023-10-18" @default.
- W2997041868 title "The Effect of Tunceli Mountain Garlic (Allium tuncelianum) and Vitamin E on Lipid Peroxidation and Antioxidant Enzyme Activities in the Intestinal Tissue of Dimethyl Benzanthracene-Administered Rats" @default.
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- W2997041868 doi "https://doi.org/10.31196/huvfd.667738" @default.
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