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- W2997104549 abstract "Familial Mediterranean Fever (FMF) is a hereditary and inflammatory disease characterized by recurrent episodes of febrile polyserosities. Herein we present a case of multiple sclerosis associated with FMF. A 40-year-old female patient on colchicine therapy since she had been diagnosed as FMF four years ago because of attacks of abdominal pain, was evaluated as for weakness in her right arm and leg. The patient also described, a few attacks of numbness involving her legs which spontaneously resolved for 2–3 days within the previous one and a half year. On neurological examination cranial area was intact. Her fundus was normal. Muscle strengths of the left upper and lower extremities were full, but at −5/5 in the right side. Deep tendon reflexes were normoactive. Plantar responses were irrelevant bilaterally. Sensory deficit was not detected. Cerebellar tests and gait were normal. On cranial MR, demyelinating ovoid plaques in periventricular white matter coursing perpendicular to the corpus callosum were observed. A contrast-enhanced plaque in the left frontal lobe was detected. Cervical MR revealed presence of plaques in the spinal cord. Her right side paresis completely resolved after pulse steroids treatment with methylprednisolone. The patient was followed up with immune modulator therapy. When abnormal findings of central nervous system are encountered in cases diagnosed as FMF apart from its typical symptoms, concomitant occurrence of multiple sclerosis should be kept in mind, and the patient should be evaluated accordingly." @default.
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- W2997104549 date "2019-10-01" @default.
- W2997104549 modified "2023-09-26" @default.
- W2997104549 title "Familial mediterranean fever and multiple sclerosis: A case report" @default.
- W2997104549 doi "https://doi.org/10.1016/j.jns.2019.10.1131" @default.
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