Matches in SemOpenAlex for { <https://semopenalex.org/work/W2997120269> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2997120269 abstract "The O-acyl isopeptide method was developed for the preparation of difficult sequence-containing peptides, whose hydrophobic nature hampers both peptide chain construction on resin and purification with HPLC after deprotection. In the O-acyl isopeptide method, the target peptide is synthesized in an O-acyl isopeptide form, which contains an O-acyl isopeptide bond instead of the native N-acyl peptide bond at a hydroxy group-containing amino acid residue, such as Ser or Thr. The hydrophilic O-acyl isopeptide can be isolated, e.g., as a lyophilized TFA salt. The target peptide can be quantitatively obtained by a final O-to-N intramolecular acyl migration reaction with exposure to neutral conditions. Additionally, the O-acyl isopeptide is important as a hydrophilic precursor peptide for biological peptide assays that are difficult to handle. This chapter describes the synthesis of such O-acyl isopeptides by stepwise and convergent Fmoc solid-phase peptide synthesis." @default.
- W2997120269 created "2020-01-10" @default.
- W2997120269 creator A5043000596 @default.
- W2997120269 date "2019-12-27" @default.
- W2997120269 modified "2023-09-25" @default.
- W2997120269 title "Synthesis of O-Acyl Isopeptides: Stepwise and Convergent Solid-Phase Synthesis" @default.
- W2997120269 cites W1975409752 @default.
- W2997120269 cites W1998535769 @default.
- W2997120269 cites W2011616487 @default.
- W2997120269 cites W2011697522 @default.
- W2997120269 cites W2024779775 @default.
- W2997120269 cites W2053058871 @default.
- W2997120269 cites W2056241835 @default.
- W2997120269 cites W2057002540 @default.
- W2997120269 cites W2059236390 @default.
- W2997120269 cites W2062583926 @default.
- W2997120269 cites W2063292917 @default.
- W2997120269 cites W2076951524 @default.
- W2997120269 cites W2092147170 @default.
- W2997120269 cites W2097663722 @default.
- W2997120269 cites W2102953802 @default.
- W2997120269 cites W2146612711 @default.
- W2997120269 cites W2149183406 @default.
- W2997120269 cites W2324898143 @default.
- W2997120269 cites W2883291618 @default.
- W2997120269 cites W2953214787 @default.
- W2997120269 doi "https://doi.org/10.1007/978-1-0716-0227-0_8" @default.
- W2997120269 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31879922" @default.
- W2997120269 hasPublicationYear "2019" @default.
- W2997120269 type Work @default.
- W2997120269 sameAs 2997120269 @default.
- W2997120269 citedByCount "0" @default.
- W2997120269 crossrefType "book-chapter" @default.
- W2997120269 hasAuthorship W2997120269A5043000596 @default.
- W2997120269 hasConcept C104317684 @default.
- W2997120269 hasConcept C161790260 @default.
- W2997120269 hasConcept C167625842 @default.
- W2997120269 hasConcept C17544334 @default.
- W2997120269 hasConcept C178790620 @default.
- W2997120269 hasConcept C185592680 @default.
- W2997120269 hasConcept C193557335 @default.
- W2997120269 hasConcept C21951064 @default.
- W2997120269 hasConcept C2776469878 @default.
- W2997120269 hasConcept C2779281246 @default.
- W2997120269 hasConcept C2779809887 @default.
- W2997120269 hasConcept C2780743229 @default.
- W2997120269 hasConcept C2781311116 @default.
- W2997120269 hasConcept C2781338088 @default.
- W2997120269 hasConcept C31684184 @default.
- W2997120269 hasConcept C39409265 @default.
- W2997120269 hasConcept C55493867 @default.
- W2997120269 hasConcept C71240020 @default.
- W2997120269 hasConcept C75079739 @default.
- W2997120269 hasConceptScore W2997120269C104317684 @default.
- W2997120269 hasConceptScore W2997120269C161790260 @default.
- W2997120269 hasConceptScore W2997120269C167625842 @default.
- W2997120269 hasConceptScore W2997120269C17544334 @default.
- W2997120269 hasConceptScore W2997120269C178790620 @default.
- W2997120269 hasConceptScore W2997120269C185592680 @default.
- W2997120269 hasConceptScore W2997120269C193557335 @default.
- W2997120269 hasConceptScore W2997120269C21951064 @default.
- W2997120269 hasConceptScore W2997120269C2776469878 @default.
- W2997120269 hasConceptScore W2997120269C2779281246 @default.
- W2997120269 hasConceptScore W2997120269C2779809887 @default.
- W2997120269 hasConceptScore W2997120269C2780743229 @default.
- W2997120269 hasConceptScore W2997120269C2781311116 @default.
- W2997120269 hasConceptScore W2997120269C2781338088 @default.
- W2997120269 hasConceptScore W2997120269C31684184 @default.
- W2997120269 hasConceptScore W2997120269C39409265 @default.
- W2997120269 hasConceptScore W2997120269C55493867 @default.
- W2997120269 hasConceptScore W2997120269C71240020 @default.
- W2997120269 hasConceptScore W2997120269C75079739 @default.
- W2997120269 hasLocation W29971202691 @default.
- W2997120269 hasOpenAccess W2997120269 @default.
- W2997120269 hasPrimaryLocation W29971202691 @default.
- W2997120269 hasRelatedWork W1097818 @default.
- W2997120269 hasRelatedWork W13654467 @default.
- W2997120269 hasRelatedWork W14966149 @default.
- W2997120269 hasRelatedWork W24196298 @default.
- W2997120269 hasRelatedWork W25110689 @default.
- W2997120269 hasRelatedWork W29261577 @default.
- W2997120269 hasRelatedWork W34170295 @default.
- W2997120269 hasRelatedWork W4445310 @default.
- W2997120269 hasRelatedWork W4991116 @default.
- W2997120269 hasRelatedWork W5279853 @default.
- W2997120269 isParatext "false" @default.
- W2997120269 isRetracted "false" @default.
- W2997120269 magId "2997120269" @default.
- W2997120269 workType "book-chapter" @default.