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• W2997133929 startingPage "39" @default.
• W2997133929 abstract "We show that negative dielectrophoresis (DEP) spectroscopy is an effective transduction mechanism of a biosensor for the detection of single nucleotide polymorphism (SNP) in a short DNA strand. We observed a frequency dependence of the negative DEP force applied by interdigitated electrodes to polystyrene microspheres (PM) with respect to changes in both the last and the second-to-last nucleotides of a single-strand DNA bound to the PM. The drift velocity of PM functionalized to single-strand DNA, which is proportional to the DEP force, was measured at the frequency range from 0.5 MHz to 2 MHz. The drift velocity was calculated using a custom-made automated software using real time image processing technique. This technology for SNP genotyping has the potential to be used in the diagnosis and the identification of genetic variants associated with diseases." @default.
• W2997133929 created "2020-01-10" @default.
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• W2997133929 date "2019-12-28" @default.
• W2997133929 modified "2023-10-03" @default.
• W2997133929 title "Nucleotide Identification in DNA Using Dielectrophoresis Spectroscopy" @default.
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• W2997133929 doi "https://doi.org/10.3390/mi11010039" @default.
• W2997133929 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7019800" @default.
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• W2997133929 hasPublicationYear "2019" @default.
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