FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2997137109> ?p ?o ?g. }

• W2997137109 endingPage "114" @default.
• W2997137109 startingPage "103" @default.
• W2997137109 abstract "Men are at a higher risk of developing bladder cancer, but women present with more advanced disease and have more unfavourable outcomes. Although epidemiologic and genetical studies have underlined the multifactorial aetiology and gender-related differences of bladder cancer, there is lack of evidence-based recommendation for gender-specific management of bladder cancer. We summarize the evidence and most recent findings on gender-specific differences in bladder cancer incidence, diagnosis, treatment and outcome, spotlighting the gender disparities in genetic and hormonal risk factors, pelvic anatomy, diagnostic setting and surgical choices. We reviewed the literature published on PubMed between 1981 and 2018. Males have a threefold to fourfold higher risk of bladder cancer as compared to females; however, women have higher stage-for-stage mortality, being diagnosed with more advanced disease, mostly due to a delay in haematuria evaluation. Numerous studies indicate an increased risk of disease recurrence or progression in women with non-muscle-invasive bladder cancer treated with trans-urethral resection, with or without intravesical chemotherapy or immunotherapy, compared to males. In particular, recent molecular evidence show that there is an excess of female Ta mutant tumours. At the time of radical cystectomy, women have a significantly longer length of hospital stay, operative time, higher blood loss and higher 90-day mortality and perioperative complication rate. Moreover, females are less likely to receive a continent diversion. Future research should guarantee greater inclusion of women in trials and focus on improving the effectiveness of therapies in women, perhaps exploring different therapeutic approaches in men and women. Specific data on functional and oncological outcomes can be analysed to define predictive factors able to guide the surgeon in decisions based on evidence. It is urgently needed to limit gender-related discrepancies in early diagnosis and treatment of bladder cancer. Public awareness and bladder cancer female patients’ consciousness on gender inequalities must be similarly uprisen." @default.
• W2997137109 created "2020-01-10" @default.
• W2997137109 creator A5031552764 @default.
• W2997137109 creator A5039039181 @default.
• W2997137109 creator A5047097708 @default.
• W2997137109 date "2019-12-23" @default.
• W2997137109 modified "2023-10-16" @default.
• W2997137109 title "Spotlight on gender-specific disparities in bladder cancer" @default.
• W2997137109 cites W1271572098 @default.
• W2997137109 cites W128672782 @default.
• W2997137109 cites W1512451698 @default.
• W2997137109 cites W1711618159 @default.
• W2997137109 cites W1757407923 @default.
• W2997137109 cites W1857623871 @default.
• W2997137109 cites W1894805572 @default.
• W2997137109 cites W1965165240 @default.
• W2997137109 cites W1968269954 @default.
• W2997137109 cites W1970354784 @default.
• W2997137109 cites W1972918275 @default.
• W2997137109 cites W1975394376 @default.
• W2997137109 cites W1978777696 @default.
• W2997137109 cites W1979494290 @default.
• W2997137109 cites W1981008728 @default.
• W2997137109 cites W1982255246 @default.
• W2997137109 cites W1984149150 @default.
• W2997137109 cites W1984967636 @default.
• W2997137109 cites W1989906144 @default.
• W2997137109 cites W1993238162 @default.
• W2997137109 cites W1995844238 @default.
• W2997137109 cites W1997112627 @default.
• W2997137109 cites W2000117804 @default.
• W2997137109 cites W2000280612 @default.
• W2997137109 cites W2003657718 @default.
• W2997137109 cites W2003886652 @default.
• W2997137109 cites W2011128044 @default.
• W2997137109 cites W2013861646 @default.
• W2997137109 cites W2014803533 @default.
• W2997137109 cites W2017485992 @default.
• W2997137109 cites W2017743487 @default.
• W2997137109 cites W2019425436 @default.
• W2997137109 cites W2023543764 @default.
• W2997137109 cites W2024653240 @default.
• W2997137109 cites W2026403310 @default.
• W2997137109 cites W2028583450 @default.
• W2997137109 cites W2028758612 @default.
• W2997137109 cites W2028807911 @default.
• W2997137109 cites W2030461848 @default.
• W2997137109 cites W2030925715 @default.
• W2997137109 cites W2033575841 @default.
• W2997137109 cites W2034889041 @default.
• W2997137109 cites W2041952735 @default.
• W2997137109 cites W2042134048 @default.
• W2997137109 cites W2042425867 @default.
• W2997137109 cites W2044545297 @default.
• W2997137109 cites W2046134348 @default.
• W2997137109 cites W2047741671 @default.
• W2997137109 cites W2051611351 @default.
• W2997137109 cites W2056295477 @default.
• W2997137109 cites W2056810321 @default.
• W2997137109 cites W2064271157 @default.
• W2997137109 cites W2065151446 @default.
• W2997137109 cites W2065541507 @default.
• W2997137109 cites W2075126653 @default.
• W2997137109 cites W2078075411 @default.
• W2997137109 cites W2080864753 @default.
• W2997137109 cites W2083929133 @default.
• W2997137109 cites W2084234730 @default.
• W2997137109 cites W2088815224 @default.
• W2997137109 cites W2089609250 @default.
• W2997137109 cites W2090308476 @default.
• W2997137109 cites W2097749048 @default.
• W2997137109 cites W2098614234 @default.
• W2997137109 cites W2114290814 @default.
• W2997137109 cites W2115519313 @default.
• W2997137109 cites W2116112878 @default.
• W2997137109 cites W2121633405 @default.
• W2997137109 cites W2126151070 @default.
• W2997137109 cites W2131318632 @default.
• W2997137109 cites W2133042546 @default.
• W2997137109 cites W2138312679 @default.
• W2997137109 cites W2138729913 @default.
• W2997137109 cites W2154017868 @default.
• W2997137109 cites W2154407182 @default.
• W2997137109 cites W2156777665 @default.
• W2997137109 cites W2158361504 @default.
• W2997137109 cites W2162130153 @default.
• W2997137109 cites W2165175692 @default.
• W2997137109 cites W2169994448 @default.
• W2997137109 cites W2314974605 @default.
• W2997137109 cites W2319008104 @default.
• W2997137109 cites W2345559105 @default.
• W2997137109 cites W2410023280 @default.
• W2997137109 cites W2747045298 @default.
• W2997137109 cites W2765116280 @default.
• W2997137109 cites W2768859600 @default.
• W2997137109 cites W2796127306 @default.
• W2997137109 doi "https://doi.org/10.1177/0391560319887327" @default.
• W2997137109 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31868559" @default.

• next