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• W2997138429 abstract "ABSTRACT Introduction Protein ingestion and the ensuing hyperaminoacidemia stimulates skeletal muscle protein synthesis in the postexercise period. This response facilitates muscle remodeling, which is important during intensified training. The aim of this study was to determine whether supplementation with α-lactalbumin (LA), with high leucine and tryptophan contents, would improve responses to short periods of intensified aerobic training compared with supplementation with an isonitrogenous quantity of collagen peptides (CP). Methods Endurance-trained participants (5 male, 6 female, 24 ± 4 yr, V˙O 2 = 53.2 ± 9.1 mL·kg −1 ·min −1 , peak power output = 320 ± 48 W; means ± SD) consumed a controlled diet (1.0 g·kg −1 ·d −1 protein) and refrained from habitual training for 11 d while taking part in this double-blind randomized, crossover trial. The two intervention phases, which consisted of brief intensified training (4 × 4-min cycling intervals at 70% of peak power output on 3 consecutive days) combined with the ingestion of LA or CP supplements after exercise (20 g) and before sleep (40 g), were separated by 4 d of washout without protein supplementation (i.e., the control phase). In response to each phase, myofibrillar (MyoPS), sarcoplasmic protein synthesis (SarcPS) rates (via 2 H 2 O ingestion) and parameters of sleep quality were measured. Results LA ingestion increased plasma leucine ( P < 0.001) and tryptophan concentrations ( P < 0.001) relative to CP. Intensified training increased MyoPS and SarcPS above the washout phase in LA- and CP-supplemented phases ( P < 0.01), with increases being 13% ± 5% and 5% ± 7% greater with LA than CP for MyoPS ( P < 0.01) and SarcPS, respectively ( P < 0.01). Conclusions Despite an isonitrogenous diet, protein synthesis was enhanced to a greater extent when trained participants consumed LA compared with CP during intensified aerobic training, suggesting that protein quality is an important consideration for endurance-trained athletes aiming to augment adaption to exercise training." @default.
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• W2997138429 date "2019-12-31" @default.
• W2997138429 modified "2023-09-27" @default.
• W2997138429 title "Lactalbumin, Not Collagen, Augments Muscle Protein Synthesis with Aerobic Exercise" @default.
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• W2997138429 doi "https://doi.org/10.1249/mss.0000000000002253" @default.
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