FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2997156811> ?p ?o ?g. }

• W2997156811 abstract "Abstract Embryos of the annual killifish Austrofundulus limnaeus are the most anoxia-tolerant vertebrate. Annual killifish inhabit ephemeral ponds, producing drought and anoxia-tolerant embryos, which allows the species to persist generation after generation. Anoxia tolerance and physiology vary by developmental stage, creating a unique opportunity for comparative study within the species. A recent study of small ncRNA expression in A . limnaeus embryos in response to anoxia and aerobic recovery revealed small ncRNAs with expression patterns that suggest a role in supporting anoxia tolerance. MitosRNAs, small ncRNAs derived from the mitochondrial genome, emerged as an interesting group of these sequences. MitosRNAs derived from mitochondrial tRNAs were differentially expressed in developing embryos and isolated cells exhibiting extreme anoxia tolerance. In this study we focus on expression of mitosRNAs derived from tRNA-cysteine, and their subcellular and organismal localization in order to consider possible function. These tRNA-cys mitosRNAs appear enriched in the mitochondria, particularly near the nucleus, and also appear to be present in the cytoplasm. We provide evidence that mitosRNAs are generated in the mitochondria in response to anoxia, though the precise mechanism of biosynthesis remains unclear. MitosRNAs derived from tRNA-cys localize to numerous tissues, and increase in the anterior brain during anoxia. We hypothesize that these RNAs may play a role in regulating gene expression that supports extreme anoxia tolerance." @default.
• W2997156811 created "2020-01-10" @default.
• W2997156811 creator A5017124853 @default.
• W2997156811 creator A5044567580 @default.
• W2997156811 creator A5063100950 @default.
• W2997156811 date "2019-12-24" @default.
• W2997156811 modified "2023-10-12" @default.
• W2997156811 title "MitosRNAs and extreme anoxia tolerance in embryos of the annual killifish Austrofundulus limnaeus" @default.
• W2997156811 cites W1490579006 @default.
• W2997156811 cites W1832399013 @default.
• W2997156811 cites W1896050447 @default.
• W2997156811 cites W1969570431 @default.
• W2997156811 cites W1973834182 @default.
• W2997156811 cites W1993252596 @default.
• W2997156811 cites W1996712185 @default.
• W2997156811 cites W2026550718 @default.
• W2997156811 cites W2050964462 @default.
• W2997156811 cites W2056831129 @default.
• W2997156811 cites W2058615001 @default.
• W2997156811 cites W2065129911 @default.
• W2997156811 cites W2065596509 @default.
• W2997156811 cites W2069639121 @default.
• W2997156811 cites W2072404306 @default.
• W2997156811 cites W2077928306 @default.
• W2997156811 cites W2084746240 @default.
• W2997156811 cites W2087463572 @default.
• W2997156811 cites W2087921665 @default.
• W2997156811 cites W2089582877 @default.
• W2997156811 cites W2097331197 @default.
• W2997156811 cites W2098981111 @default.
• W2997156811 cites W2100702807 @default.
• W2997156811 cites W2102186047 @default.
• W2997156811 cites W2103677266 @default.
• W2997156811 cites W2105813106 @default.
• W2997156811 cites W2106477546 @default.
• W2997156811 cites W2107708548 @default.
• W2997156811 cites W2113194941 @default.
• W2997156811 cites W2117640689 @default.
• W2997156811 cites W2119931353 @default.
• W2997156811 cites W2130105614 @default.
• W2997156811 cites W2137665434 @default.
• W2997156811 cites W2141581548 @default.
• W2997156811 cites W2147295203 @default.
• W2997156811 cites W2148224382 @default.
• W2997156811 cites W2150926065 @default.
• W2997156811 cites W2152908368 @default.
• W2997156811 cites W2156506178 @default.
• W2997156811 cites W2179438025 @default.
• W2997156811 cites W2181949614 @default.
• W2997156811 cites W2186949423 @default.
• W2997156811 cites W2194725007 @default.
• W2997156811 cites W2262003432 @default.
• W2997156811 cites W2270590066 @default.
• W2997156811 cites W2295446298 @default.
• W2997156811 cites W2403973474 @default.
• W2997156811 cites W2507861162 @default.
• W2997156811 cites W2536750967 @default.
• W2997156811 cites W2562613588 @default.
• W2997156811 cites W2578480980 @default.
• W2997156811 cites W2612614793 @default.
• W2997156811 cites W2744418771 @default.
• W2997156811 cites W2765116800 @default.
• W2997156811 cites W2791077787 @default.
• W2997156811 cites W2884073635 @default.
• W2997156811 cites W2916345918 @default.
• W2997156811 cites W2948283814 @default.
• W2997156811 cites W2949140191 @default.
• W2997156811 cites W2950847039 @default.
• W2997156811 doi "https://doi.org/10.1038/s41598-019-56231-2" @default.
• W2997156811 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6930250" @default.
• W2997156811 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31874982" @default.
• W2997156811 hasPublicationYear "2019" @default.
• W2997156811 type Work @default.
• W2997156811 sameAs 2997156811 @default.
• W2997156811 citedByCount "4" @default.
• W2997156811 countsByYear W29971568112021 @default.
• W2997156811 countsByYear W29971568112022 @default.
• W2997156811 countsByYear W29971568112023 @default.
• W2997156811 crossrefType "journal-article" @default.
• W2997156811 hasAuthorship W2997156811A5017124853 @default.
• W2997156811 hasAuthorship W2997156811A5044567580 @default.
• W2997156811 hasAuthorship W2997156811A5063100950 @default.
• W2997156811 hasBestOaLocation W29971568111 @default.
• W2997156811 hasConcept C196843134 @default.
• W2997156811 hasConcept C2779153044 @default.
• W2997156811 hasConcept C28859421 @default.
• W2997156811 hasConcept C2909208804 @default.
• W2997156811 hasConcept C505870484 @default.
• W2997156811 hasConcept C54355233 @default.
• W2997156811 hasConcept C86803240 @default.
• W2997156811 hasConcept C95444343 @default.
• W2997156811 hasConceptScore W2997156811C196843134 @default.
• W2997156811 hasConceptScore W2997156811C2779153044 @default.
• W2997156811 hasConceptScore W2997156811C28859421 @default.
• W2997156811 hasConceptScore W2997156811C2909208804 @default.
• W2997156811 hasConceptScore W2997156811C505870484 @default.
• W2997156811 hasConceptScore W2997156811C54355233 @default.
• W2997156811 hasConceptScore W2997156811C86803240 @default.
• W2997156811 hasConceptScore W2997156811C95444343 @default.
• W2997156811 hasFunder F4320306076 @default.

• next