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- W2997182803 abstract "Introduction: This study was designed to analyze the risk factors associated with postoperative pancreatic fistula (PF) using a large cohort registered in the Korean Tumor Registry System: Biliary-Pancreas (KOTUS-BP). Method: Sixty-two surgeons from 18 tertiary hospitals participated in the KOTUS-BP cohort. Patients who underwent pancreaticoduodenectomy for periampullary neoplasia were identified in the database. We analyzed the patients’ characteristics, preoperative data, operation method, and postoperative outcomes including PF. Result: Of the 4,846 patients, 179 patients with missing records of PF were excluded. A total of 4,667 patients were enrolled in this study. Postoperatively, 298 patients (6.4%) had experienced clinically relevant pancreatic fistula (CR-PF). In multivariate analysis, female sex, pancreatic cancer, and lymphovascular invasion were statistically significantly protective factor of CR-PF (p = 0.006, p < 0.001, p = 0.039, respectively). However, pylorus preservation was associated with CR-PF (p <0.001). Conclusion: The analysis of large-scale multicenter cohort data showed that female gender, pancreatic cancer, conventional pancreaticoduodenectomy, and lymphovascular invasion were associated with decreased CR-PF incidence." @default.
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- W2997182803 date "2019-01-01" @default.
- W2997182803 modified "2023-10-14" @default.
- W2997182803 title "Risk Factors of Postoperative Pancreatic Fistula after Pancreaticoduodenectomy: A Multicenter Cohort Study" @default.
- W2997182803 doi "https://doi.org/10.1016/j.hpb.2019.10.2235" @default.
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