Matches in SemOpenAlex for { <https://semopenalex.org/work/W2997186344> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2997186344 endingPage "S239" @default.
- W2997186344 startingPage "S239" @default.
- W2997186344 abstract "Introduction: Preoperative neutrophil to lymphocyte ratio (NLR) is a marker of inflammation previously found to be associated with poor post-operative outcomes. Our objective was to investigate the association between NLR with the post-operative outcomes in patients undergoing resection of colorectal liver metastases (CRLM). Method: Consecutive patients who underwent complete resection of CRLM at Rabin Medical Center and Carmel Medical Center between 2007-2017 were included. NLR was calculated before resection and tested for association with post-operative outcomes and survival. Major complication was classified as Clavien-Dindo >2. Result: This study included 381 cases of CRLM resection with a median age of 65 years (IQR:56-72) and 59% (226) were female. The median follow-up was 45 months (IQR:24-75). Preoperative chemotherapy was administered in 67%(256) of cases, 39%(147) of cases were performed laparoscopically, and 42% (158) were major hepatectomies. Intra-operative blood products were administered in 100 cases (26%). Major complications occurred in 14%(52) of cases, while the 30- and 90-day mortality rates were 2% (8) and 3% (13) respectively. Female gender and laparoscopic resection were found to be associated with reduced risk for major complications (OR=0.413,95%CI 0.2-0.8,p=0.009;and OR=0.412,95%CI 0.2-0.8,p=0.017,respectively). Administration of ≥2units blood and NLR≥2.5 were found to be associated with higher risk of major complications (OR=2.198,95%CI 1.1-4.4,p=0.029; and OR=2.712, 95% CI 1.4-5.2, p=0.002,respectively). The median overall survival for patients with NLR >5 was 43 months (95% CI:22-65) versus 59 months (95% CI:51-67) for the patients with NLR<5 (p=0.02). Conclusion: The NLR may have a role in predicting post-operative complications following liver resection for CRLM, and may also predict poor prognosis. This biomarker should be further explored in a prospective trial." @default.
- W2997186344 created "2020-01-10" @default.
- W2997186344 creator A5003379685 @default.
- W2997186344 creator A5011126174 @default.
- W2997186344 creator A5012102077 @default.
- W2997186344 creator A5017804822 @default.
- W2997186344 creator A5032914204 @default.
- W2997186344 creator A5036434395 @default.
- W2997186344 creator A5057967242 @default.
- W2997186344 creator A5079773574 @default.
- W2997186344 creator A5082720171 @default.
- W2997186344 creator A5088629729 @default.
- W2997186344 date "2019-01-01" @default.
- W2997186344 modified "2023-10-17" @default.
- W2997186344 title "Preoperative Neutrophil to Lymphocyte Ratio as a Predictor of Outcome in Patients Undergoing resection of Colorectal Liver Metastases– A Retrospective Multi-Center Study" @default.
- W2997186344 doi "https://doi.org/10.1016/j.hpb.2019.10.1661" @default.
- W2997186344 hasPublicationYear "2019" @default.
- W2997186344 type Work @default.
- W2997186344 sameAs 2997186344 @default.
- W2997186344 citedByCount "0" @default.
- W2997186344 crossrefType "journal-article" @default.
- W2997186344 hasAuthorship W2997186344A5003379685 @default.
- W2997186344 hasAuthorship W2997186344A5011126174 @default.
- W2997186344 hasAuthorship W2997186344A5012102077 @default.
- W2997186344 hasAuthorship W2997186344A5017804822 @default.
- W2997186344 hasAuthorship W2997186344A5032914204 @default.
- W2997186344 hasAuthorship W2997186344A5036434395 @default.
- W2997186344 hasAuthorship W2997186344A5057967242 @default.
- W2997186344 hasAuthorship W2997186344A5079773574 @default.
- W2997186344 hasAuthorship W2997186344A5082720171 @default.
- W2997186344 hasAuthorship W2997186344A5088629729 @default.
- W2997186344 hasBestOaLocation W29971863441 @default.
- W2997186344 hasConcept C121608353 @default.
- W2997186344 hasConcept C126322002 @default.
- W2997186344 hasConcept C141071460 @default.
- W2997186344 hasConcept C159110652 @default.
- W2997186344 hasConcept C167135981 @default.
- W2997186344 hasConcept C2777761686 @default.
- W2997186344 hasConcept C2778963024 @default.
- W2997186344 hasConcept C2780073493 @default.
- W2997186344 hasConcept C44249647 @default.
- W2997186344 hasConcept C526805850 @default.
- W2997186344 hasConcept C71924100 @default.
- W2997186344 hasConcept C81182388 @default.
- W2997186344 hasConcept C90924648 @default.
- W2997186344 hasConceptScore W2997186344C121608353 @default.
- W2997186344 hasConceptScore W2997186344C126322002 @default.
- W2997186344 hasConceptScore W2997186344C141071460 @default.
- W2997186344 hasConceptScore W2997186344C159110652 @default.
- W2997186344 hasConceptScore W2997186344C167135981 @default.
- W2997186344 hasConceptScore W2997186344C2777761686 @default.
- W2997186344 hasConceptScore W2997186344C2778963024 @default.
- W2997186344 hasConceptScore W2997186344C2780073493 @default.
- W2997186344 hasConceptScore W2997186344C44249647 @default.
- W2997186344 hasConceptScore W2997186344C526805850 @default.
- W2997186344 hasConceptScore W2997186344C71924100 @default.
- W2997186344 hasConceptScore W2997186344C81182388 @default.
- W2997186344 hasConceptScore W2997186344C90924648 @default.
- W2997186344 hasLocation W29971863441 @default.
- W2997186344 hasOpenAccess W2997186344 @default.
- W2997186344 hasPrimaryLocation W29971863441 @default.
- W2997186344 hasRelatedWork W1483058388 @default.
- W2997186344 hasRelatedWork W2080756964 @default.
- W2997186344 hasRelatedWork W2417961914 @default.
- W2997186344 hasRelatedWork W2474039552 @default.
- W2997186344 hasRelatedWork W2945124548 @default.
- W2997186344 hasRelatedWork W2977325287 @default.
- W2997186344 hasRelatedWork W3139267926 @default.
- W2997186344 hasRelatedWork W4305082178 @default.
- W2997186344 hasRelatedWork W4319440053 @default.
- W2997186344 hasRelatedWork W62711790 @default.
- W2997186344 hasVolume "21" @default.
- W2997186344 isParatext "false" @default.
- W2997186344 isRetracted "false" @default.
- W2997186344 magId "2997186344" @default.
- W2997186344 workType "article" @default.