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• W2997190714 abstract "To date, the vast majority of intra-vital neuroimaging systems applied in clinic and diagnostics is stationary with a rigid scanning element, requires specialized facilities and costly infrastructure. Here, we describe a simple yet radical approach for optoacoustic (photoacoustic) brain imaging in vivo using a light-weight handheld probe. It enables multispectral video-rate visualization of hemoglobin gradient changes in the cortex of adult rats induced by whisker and forelimb sensory inputs, as well as by optogenetic stimulation of intra-cortical connections. With superb penetration and molecular specificity, described here in method holds major promises for future applications in research, routine ambulatory neuroimaging, and diagnostics." @default.
• W2997190714 created "2020-01-10" @default.
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• W2997190714 date "2020-03-01" @default.
• W2997190714 modified "2023-09-23" @default.
• W2997190714 title "Visualizing cortical response to optogenetic stimulation and sensory inputs using multispectral handheld optoacoustic imaging" @default.
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• W2997190714 doi "https://doi.org/10.1016/j.pacs.2019.100153" @default.
• W2997190714 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7052434" @default.
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