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• W2997261330 abstract "Arc, a neuronal gene that is critical for synaptic plasticity, originated through the domestication of retrotransposon Gag genes and mediates intercellular messenger RNA transfer. We report high-resolution structures of retrovirus-like capsids formed by Drosophila dArc1 and dArc2 that have surface spikes and putative internal RNA-binding domains. These data demonstrate that virus-like capsid-forming properties of Arc are evolutionarily conserved and provide a structural basis for understanding their function in intercellular communication." @default.
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• W2997261330 date "2020-01-06" @default.
• W2997261330 modified "2023-10-13" @default.
• W2997261330 title "Structures of virus-like capsids formed by the Drosophila neuronal Arc proteins" @default.
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• W2997261330 doi "https://doi.org/10.1038/s41593-019-0569-y" @default.
• W2997261330 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7032958" @default.
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