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- W2997269021 endingPage "126128" @default.
- W2997269021 startingPage "126128" @default.
- W2997269021 abstract "• Formation pathways for heterocyclic aromatic amines (HAAs) are critically reviewed. • Alternative pathways based on cyclization of reactive aldehydes are proposed. • Formation and fate of these aldehydes under common cooking conditions is discussed. • Role of carbonyl-amine and carbonyl-phenol reactions on HAA formation is analyzed. Thermal food processing has many beneficial consequences, although it also produces some unintentional undesired effects, such as the formation of potentially mutagenic and carcinogenic substances. Among them, the formation of heterocyclic aromatic amines (HAAs) has been related to the declared carcinogenicity of processed meats. In spite of this importance, HAA formation pathways remain mostly unknown, which avoids the design of targeted procedures to inhibit HAA appearance. The objective of this review is to collect information recently appeared that allow advancing in the understanding of how these compounds are produced. Particularly, the possibility that aminoimidazoazarenes are produced similarly to PhIP is discussed, including their formation by cyclizations and oligomerizations of aldehydes and creatinine under usual cooking conditions. Present data suggest that HAA formation might be related to the pool of carbonyl compounds existing in foods, the food carbonylome, which can be controlled by carbonyl-trapping agents, such as amine and phenolic compounds." @default.
- W2997269021 created "2020-01-10" @default.
- W2997269021 creator A5029816808 @default.
- W2997269021 creator A5030654510 @default.
- W2997269021 date "2020-05-01" @default.
- W2997269021 modified "2023-10-17" @default.
- W2997269021 title "Formation of heterocyclic aromatic amines with the structure of aminoimidazoazarenes in food products" @default.
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