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- W2997386066 abstract "In this paper, water-soluble polysaccharides (named as NRLP) were extracted from Nitraria retusa leaves. The main structural features of NRLP were determined by High-pressure size exclusion chromatography, Fourier transform infrared and Gas Chromatography/Mass Spectrometry-Electronic Impact analysis. The in vitro and in vivo biological potential of NRLP were evaluated by measuring its antioxidant (•OH and DPPH• scavenging, total antioxidant capacity), anti-α-amylase as well as anti-inflammatory and antinociceptive activities in a mice model. NRLP was composed of Rha (33.7%), Gal (18.1%), GalA (15.0%), Glc (13.3%), Ara (13.3%), Xyl (3.8%), and GlcA (2.8%) and showed a Molecular Weight (Mw) of 23.0 kDa and a polydispersity index (PDI) of 1.66. The investigations highlighted a significant antioxidant activity (IC50 = 2.4–2.6 mg/mL) and an inhibition activity against α-amylase (IC50 = 4.55 mg/mL) in a dose-dependent manner. Further, NRLP revealed interesting anti-edematous effects and antinociceptive activities (both > 70%). These results open up new pharmacological prospects for the water-soluble polysaccharides extracted from Nitraria retusa leaves." @default.
- W2997386066 created "2020-01-10" @default.
- W2997386066 creator A5047980202 @default.
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- W2997386066 date "2019-12-26" @default.
- W2997386066 modified "2023-10-09" @default.
- W2997386066 title "Novel Antioxidant, Anti-α-Amylase, Anti-Inflammatory and Antinociceptive Water-Soluble Polysaccharides from the Aerial Part of Nitraria retusa" @default.
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- W2997386066 doi "https://doi.org/10.3390/foods9010028" @default.
- W2997386066 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7022424" @default.
- W2997386066 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31888100" @default.
- W2997386066 hasPublicationYear "2019" @default.
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