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- W2997431290 abstract "Multiple sclerosis (MS) is a demyelinating disease of the central nervous system leading to disability, especially in young patients. Ocular motor manifestations in MS can occur acutely in relapse or chronically, the last as a consequence of previous relapses or as a chronic course of the disease. This talk encompasses the spectrum of ocular motor disorders in patients with MS emphasizing prevalence, examination findings, diagnostic features, functional consequences, classification of MS course, and management of these disturbances of ocular motility. The most frequent and specific acute ocular motor manifestation is uni- or bilateral internuclear ophthalmoplegia (INO). The most frequent chronic manifestations include INO and cerebellar ocular motor disorders such as gaze-evoked nystagmus, saccadic hypermetria, and lack of vestibulo-ocular reflex inhibition. The most disabling syndrome is pendular nystagmus. The high prevalence of ocular motor manifestations in MS emphasizes the importance of neuroophthalmological examination. Because chronic manifestations are mostly silent, a systematic investigation of the most common manifestations should be performed in daily practice. Appropriate treatment may improve visual outcome in some of these ocular motor disorders." @default.
- W2997431290 created "2020-01-10" @default.
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- W2997431290 date "2019-10-01" @default.
- W2997431290 modified "2023-09-25" @default.
- W2997431290 title "Ocular motility disorders with special emphasis on multiple sclerosis" @default.
- W2997431290 doi "https://doi.org/10.1016/j.jns.2019.10.137" @default.
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