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- W2997453896 abstract "Seizures are a frequent manifestation of central nervous system disorders in patients infected with HIV. In the present study, the aim of the study was to determine the prevalence of seizure among AIDS patients in Iran. In this cross-sectional study, patients who were diagnosed with HIV infection admitted to Rasoul-e-Akram Hospital between 2011 and 2016 were assessed. All study information was extracted from the hospital recorded files. In this study, 443 patients with HIV infection. In terms of sex distribution, 325 cases (73.3%) were men and 118 cases (26.7%) were women. Of the 443 patients, only 4 patients (3 cases of male and 1 female) had a history of seizure during the course of the disease, indicating a 0.9% prevalence of seizure and epilepsy among HIV patients. Seizure was more prevalent as a neurological manifestation of AIDS in the second and third decades of life. Patients suffering seizure had significantly lower CD4 count. There was no relationship between seizure incidence and hepatitis B and C infection. The seizure was controlled with Levetiracetam or sodium valproate regimens. The occurrence of seizure in HIV patients has an etiologic relationship with toxoplasmosis as well as with cytomegalovirus infections leading to encephalitis. The prevalence of seizure in AIDS patients in our community is estimated to be 0.9%, which is prevalent in men and in the second and third decades of life. Patients who suffer seizure display lower CD4 positive counts indicating seizure occurrence in the end stages of the disease." @default.
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- W2997453896 date "2019-10-01" @default.
- W2997453896 modified "2023-09-25" @default.
- W2997453896 title "An overview on the epidemiology of aids and its related seizure in Iranian society" @default.
- W2997453896 doi "https://doi.org/10.1016/j.jns.2019.10.1773" @default.
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