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- W2997473540 abstract "Cell membrane modification is important for tissue engineering, cell-based therapies, and cell biology studies. Recently, oligonucleotides have attracted considerable attention to remodel and functionalize live cell membranes. In particular, a type of amphiphilic lipid–oligonucleotide conjugates have been rationally designed and synthesized for this purpose. These conjugates have enabled a rapid, straightforward, and efficient cell membrane modification. Taking advantage of highly precise and programmable self-assembly of DNAs and RNAs, lipid–oligonucleotide conjugates have been used for membrane bioanalysis, therapeutics, building artificial membrane structures, and regulating cell–surface and cell–cell interactions. In this review, we have summarized the current knowledge in the design, synthesis, and regulating membrane properties of lipid–oligonucleotide conjugates. In addition, their state-of-the-art applications in cell membrane engineering and bioanalysis have been illustrated." @default.
- W2997473540 created "2020-01-10" @default.
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- W2997473540 date "2020-03-01" @default.
- W2997473540 modified "2023-10-14" @default.
- W2997473540 title "Lipid–oligonucleotide conjugates for simple and efficient cell membrane engineering and bioanalysis" @default.
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- W2997473540 doi "https://doi.org/10.1016/j.cobme.2019.12.006" @default.
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