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- W2997474436 abstract "Recombinant adeno-associated virus (rAAV) is a widely used tool for gene delivery due to its high efficiency to transduce postmitotic cells. However, host immune reactions targeting AAV can limit its therapeutic benefit in clinical applications. While most studies focused on adaptive immunity, initial innate immune responses are the first line of defense against viral vectors and help modulate subsequent adaptive immune responses. The understanding of innate immune responses to AAV can potentially improve safety and therapeutic efficiency of AAV. This article provides an overview of innate immune responses to AAV vectors." @default.
- W2997474436 created "2020-01-10" @default.
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- W2997474436 date "2019-01-01" @default.
- W2997474436 modified "2023-09-27" @default.
- W2997474436 title "Innate Immune Response Following AAV Administration" @default.
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- W2997474436 doi "https://doi.org/10.1007/978-3-030-27378-1_27" @default.
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