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- W2997478942 abstract "Purpose To investigate the short-term effects of the partial ventriculectomy (ressection of lateral wall associated to mitral annuloplasty) on cardiac mechanics, contractility, shape and geometry of the left ventricle (LV). Methods Eleven male patients with severe congestive heart failure due to dilated cardiomyopathy were studied. The mean age was 51±7 years and the functional class was III (five patients) or IV (six patients) before the surgery. Patients were evaluated before and at 17±4 days after the surgery by simultaneous LV pressure and echocardiographic data. End-diastolic pressure (EDP mmHg), wall stress (EDS g/cm) and diameter (EDD cm); endsystolic wall stress (ESS) and diameter (ESD), fractional shortening (FS %) and maximal elastance (E max mmHg/ cm/s); the diastolic slope of the pressure-diameter (Kp mmHg/cm) and stress-strain (Km g/cm2) loops; shape (L/ EDD, adimensional, where L is the LV long axis) and geometry (Th/EDD, adimensional, where TH is the LV diastolic thickness) were obtained. Results 1) The ressected muscle fragments (diamond shape) were 10.8±1.3cm in lenght and 5±0.6cm in width; 2) all patients were discharged from hospital (15-29 days) in class I (eight cases), II (two), and III (one); 3) it was observed a decrease in EDP (24.3±7.7 x 17.5±3.2, p=0.016); in EDD (8.0±0.7 x 7.2±0.8, p=0.002); in EDS (57.9±26.8 x 37.4±19.2, p=0.005); in ESS (199±46.9 x 102.8±33.1, p=0.004); in ESD (7.1±0.7 x 5.7±0.8, p<0.001); in Kp (22.3±15.9 x 11.5±6.9, p=0.014); and in Km (467.4±212 x 214.6±87.4, p=0.01); and, 4) it was noted an increase in FS (11.5±1.8 x 19.8±3.9, p<0.001); in E max (13.8±2.2 x 18.6±3.2, p<0.001); and in L/EDD (1.32±0.1 x 1.47±0.13, p<0.007) and Th/Dd (0.11±0.04 x 0.17±0.08, p<0.038). Conclusion The partial ventriculectomy showed multiple significant beneficial effects in these dilated myopathic hearts." @default.
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- W2997478942 title "Efeitos da ventriculectomia parcial nas propriedades mecânicas, forma e geometria do ventrículo esquerdo em portadores de cardiomiopatia dilatada" @default.
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