Matches in SemOpenAlex for { <https://semopenalex.org/work/W2997479931> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2997479931 endingPage "1774" @default.
- W2997479931 startingPage "1767" @default.
- W2997479931 abstract "Mangosteen (Garcinia mangostana Linn.) rind is known for its anti-inflammatory activity. Inflammation of local tissue can be overcome by topical administration of dosage forms. In an effort to improve the quality of topical drug delivery, nanoparticle technology can be an option.The purpose of this study is to determine the activity of gel and nanoemulgel dosage forms containing fractions of mangosteen rind extract (n-hexane: ethyl acetate). The gel dosage form of mangosteen rind fractions was successfully prepared. Its physical and chemical properties were evaluated, and the results were within the expected range. The spreadibility of the formulations was between 5-7cm and the pH was between 4.5 and 6.5.The 0.0625% and 0.125% mangosteen rind fraction concentrations are the formulas by which nanoemulgel was successfully formed, resulting in non-separating phases, percent transmittance of 96.997 ± 0.137% and 94.253 ± 0.134% respectively, particle size of 17.437 ± 0.427 and 17.240 ± 0.276 nm; potential zeta of 5.183 ± 0.202 and -10.143 ± 0.238. In the inflammatory test of carrageenan induced laboratory mice, nanoemulgel containing 0.0625% and 0.125% mangosteen rind fraction concentrations produced better percent inhibition (p<0.05) compared to gel containing 0.1%, 0.5%, and 1% mangosteen rind fraction concentrationsin the 90th minute, but the difference was not significant in the 120thminute through the end of thetest. The nanoemulgel containing 0.0625% and 0.125% mangosteen rind fraction concentrations have an unsignificant difference in results (p>0.05) when compared to the reference drug (diclofenac sodium) in the 90th minute." @default.
- W2997479931 created "2020-01-10" @default.
- W2997479931 creator A5017194158 @default.
- W2997479931 creator A5024236971 @default.
- W2997479931 creator A5040499439 @default.
- W2997479931 creator A5040915883 @default.
- W2997479931 creator A5054884249 @default.
- W2997479931 date "2019-12-27" @default.
- W2997479931 modified "2023-10-10" @default.
- W2997479931 title "Anti-Inflammatory Activity of Mangosteen (Garcinia Mangostana Linn.) Rind Extract Nanoemulgel and Gel Dosage Forms" @default.
- W2997479931 cites W1981819970 @default.
- W2997479931 cites W2016281184 @default.
- W2997479931 cites W2027321893 @default.
- W2997479931 cites W2036267752 @default.
- W2997479931 cites W2049776803 @default.
- W2997479931 cites W2120857280 @default.
- W2997479931 cites W2165674962 @default.
- W2997479931 cites W2168285948 @default.
- W2997479931 cites W4240821889 @default.
- W2997479931 doi "https://doi.org/10.13005/bpj/1807" @default.
- W2997479931 hasPublicationYear "2019" @default.
- W2997479931 type Work @default.
- W2997479931 sameAs 2997479931 @default.
- W2997479931 citedByCount "7" @default.
- W2997479931 countsByYear W29974799312021 @default.
- W2997479931 countsByYear W29974799312022 @default.
- W2997479931 countsByYear W29974799312023 @default.
- W2997479931 crossrefType "journal-article" @default.
- W2997479931 hasAuthorship W2997479931A5017194158 @default.
- W2997479931 hasAuthorship W2997479931A5024236971 @default.
- W2997479931 hasAuthorship W2997479931A5040499439 @default.
- W2997479931 hasAuthorship W2997479931A5040915883 @default.
- W2997479931 hasAuthorship W2997479931A5054884249 @default.
- W2997479931 hasBestOaLocation W29974799311 @default.
- W2997479931 hasConcept C149629883 @default.
- W2997479931 hasConcept C155672457 @default.
- W2997479931 hasConcept C171250308 @default.
- W2997479931 hasConcept C185592680 @default.
- W2997479931 hasConcept C192562407 @default.
- W2997479931 hasConcept C2777077568 @default.
- W2997479931 hasConcept C2779858419 @default.
- W2997479931 hasConcept C2781227287 @default.
- W2997479931 hasConcept C2909826119 @default.
- W2997479931 hasConcept C31903555 @default.
- W2997479931 hasConcept C43617362 @default.
- W2997479931 hasConcept C556039675 @default.
- W2997479931 hasConcept C71924100 @default.
- W2997479931 hasConcept C86181022 @default.
- W2997479931 hasConceptScore W2997479931C149629883 @default.
- W2997479931 hasConceptScore W2997479931C155672457 @default.
- W2997479931 hasConceptScore W2997479931C171250308 @default.
- W2997479931 hasConceptScore W2997479931C185592680 @default.
- W2997479931 hasConceptScore W2997479931C192562407 @default.
- W2997479931 hasConceptScore W2997479931C2777077568 @default.
- W2997479931 hasConceptScore W2997479931C2779858419 @default.
- W2997479931 hasConceptScore W2997479931C2781227287 @default.
- W2997479931 hasConceptScore W2997479931C2909826119 @default.
- W2997479931 hasConceptScore W2997479931C31903555 @default.
- W2997479931 hasConceptScore W2997479931C43617362 @default.
- W2997479931 hasConceptScore W2997479931C556039675 @default.
- W2997479931 hasConceptScore W2997479931C71924100 @default.
- W2997479931 hasConceptScore W2997479931C86181022 @default.
- W2997479931 hasIssue "04" @default.
- W2997479931 hasLocation W29974799311 @default.
- W2997479931 hasOpenAccess W2997479931 @default.
- W2997479931 hasPrimaryLocation W29974799311 @default.
- W2997479931 hasRelatedWork W1517840085 @default.
- W2997479931 hasRelatedWork W1554720925 @default.
- W2997479931 hasRelatedWork W2553149718 @default.
- W2997479931 hasRelatedWork W2969615661 @default.
- W2997479931 hasRelatedWork W2991406370 @default.
- W2997479931 hasRelatedWork W3043752014 @default.
- W2997479931 hasRelatedWork W3133800563 @default.
- W2997479931 hasRelatedWork W3211848926 @default.
- W2997479931 hasRelatedWork W4248481166 @default.
- W2997479931 hasRelatedWork W4317434252 @default.
- W2997479931 hasVolume "12" @default.
- W2997479931 isParatext "false" @default.
- W2997479931 isRetracted "false" @default.
- W2997479931 magId "2997479931" @default.
- W2997479931 workType "article" @default.