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- W2997509995 abstract "Global developmental delay (GDD) is defined as significant delay in one or more developmental domains. Evaluation of a child with developmental delay is important not only because it allows early diagnosis and treatment but also helpful for parental counseling regarding the outcome of their child and to identify any possible risk of recurrence in the siblings. Magnetic Resonance Imaging (MRI) is the best modality to investigate such patients. To study the prevalence of normal and abnormal MRI in pediatric patients presenting with GDD and further categorize the abnormal MRI based on its morphological features. It is a retrospective, observational study of MRI Brain in 98 pediatric patients (57 Males and 41 Females) aged between 3 months–12 years; presenting with developmental delay. MRI brain was done on 3T Siemens with appropriate sequences and planes after making the child sleep/sedated/ anesthetized. Various anatomical structures like Ventricles, Corpus callosum, etc were systematically assessed. Normal MRI findings were seen in 37% cases and 61% had abnormal findings of which the proportion of 62.2%. The ventricles and white matter mainly the corpus callosum were the most commonly affected anatomical structures. In 5 (3%) patients, MRI gave direct diagnosis and in 32 (18.8%) MRI suggested diagnosis which was confirmed by further investigation. The clinical diagnosis of developmental delay should not be the end point, but rather a springboard for an effective search for causal factors. MRI is the best investigation with a high yield in such patients." @default.
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- W2997509995 date "2019-10-01" @default.
- W2997509995 modified "2023-09-26" @default.
- W2997509995 title "Magnetic resonance imaging (MRI) evaluation of global developmental delay in pediatric patients: A retrospective study" @default.
- W2997509995 doi "https://doi.org/10.1016/j.jns.2019.10.310" @default.
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