FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2997571627> ?p ?o ?g. }

• W2997571627 endingPage "116" @default.
• W2997571627 startingPage "116" @default.
• W2997571627 abstract "Objective: Growth differentiation factor-8 (GDF8), also known as myostatin, is a member of the transforming growth factor-β superfamily that inhibits skeletal muscle growth. We aimed to investigate the association between GDF8 and peak troponin I levels after acute myocardial infarction (AMI). Methods: All consecutive patients admitted from June 2016 to February 2018 for type 1 AMI in the Coronary Care Unit of University Hospital of Dijon Bourgogne (France) were included in our prospective study. Blood samples were harvested on admission, and serum levels of GDF8 were measured using a commercially available enzyme-linked immunosorbent assay kit. Results: Among the 296 patients with type 1 AMI, median age was 68 years and 27% were women. GDF8 levels (median (IQR) = 2375 ng/L) were negatively correlated with age, sex and diabetes (p < 0.001 for all). GDF8 levels were higher in patients with in-hospital ventricular tachycardia or fibrillation (VT/VF) than those without in-hospital VT/VF. GDF8 was positively correlated with troponin I peak (r = 0.247; p < 0.001). In multivariate linear regression analysis, log GDF8 (OR: 21.59; 95% CI 34.08–119.05; p < 0.001) was an independent predictor of troponin I peak. Conclusions: These results suggest that GDF8 levels could reflect the extent of myocardial damage during AMI, similar to peak troponin I, which is currently used to estimate infarct size. Further studies are needed to elucidate the underlying mechanisms linking the GDF8 cytokine with troponin I levels." @default.
• W2997571627 created "2020-01-10" @default.
• W2997571627 creator A5032540752 @default.
• W2997571627 creator A5038949992 @default.
• W2997571627 creator A5041800562 @default.
• W2997571627 creator A5053757213 @default.
• W2997571627 creator A5055720214 @default.
• W2997571627 creator A5061174945 @default.
• W2997571627 creator A5064783426 @default.
• W2997571627 creator A5074647755 @default.
• W2997571627 date "2019-12-31" @default.
• W2997571627 modified "2023-10-17" @default.
• W2997571627 title "Growth Differentiation Factor-8 (GDF8)/Myostatin Is a Predictor of Troponin I Peak and a Marker of Clinical Severity after Acute Myocardial Infarction" @default.
• W2997571627 cites W1912438198 @default.
• W2997571627 cites W1965705624 @default.
• W2997571627 cites W1975544443 @default.
• W2997571627 cites W1994270208 @default.
• W2997571627 cites W2034279294 @default.
• W2997571627 cites W2054027756 @default.
• W2997571627 cites W2055891387 @default.
• W2997571627 cites W2064665289 @default.
• W2997571627 cites W2074161753 @default.
• W2997571627 cites W2087313135 @default.
• W2997571627 cites W2104321619 @default.
• W2997571627 cites W2114796514 @default.
• W2997571627 cites W2132813206 @default.
• W2997571627 cites W2144331482 @default.
• W2997571627 cites W2157467578 @default.
• W2997571627 cites W2158018315 @default.
• W2997571627 cites W2164525276 @default.
• W2997571627 cites W2165868509 @default.
• W2997571627 cites W2291920449 @default.
• W2997571627 cites W2292128548 @default.
• W2997571627 cites W2326339004 @default.
• W2997571627 cites W2337739010 @default.
• W2997571627 cites W2428794379 @default.
• W2997571627 cites W2545266774 @default.
• W2997571627 cites W2625982686 @default.
• W2997571627 cites W2754054868 @default.
• W2997571627 cites W2889347720 @default.
• W2997571627 cites W2892127723 @default.
• W2997571627 cites W2943699765 @default.
• W2997571627 cites W4211104669 @default.
• W2997571627 cites W4292856638 @default.
• W2997571627 doi "https://doi.org/10.3390/jcm9010116" @default.
• W2997571627 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7019567" @default.
• W2997571627 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31906236" @default.
• W2997571627 hasPublicationYear "2019" @default.
• W2997571627 type Work @default.
• W2997571627 sameAs 2997571627 @default.
• W2997571627 citedByCount "11" @default.
• W2997571627 countsByYear W29975716272020 @default.
• W2997571627 countsByYear W29975716272021 @default.
• W2997571627 countsByYear W29975716272022 @default.
• W2997571627 countsByYear W29975716272023 @default.
• W2997571627 crossrefType "journal-article" @default.
• W2997571627 hasAuthorship W2997571627A5032540752 @default.
• W2997571627 hasAuthorship W2997571627A5038949992 @default.
• W2997571627 hasAuthorship W2997571627A5041800562 @default.
• W2997571627 hasAuthorship W2997571627A5053757213 @default.
• W2997571627 hasAuthorship W2997571627A5055720214 @default.
• W2997571627 hasAuthorship W2997571627A5061174945 @default.
• W2997571627 hasAuthorship W2997571627A5064783426 @default.
• W2997571627 hasAuthorship W2997571627A5074647755 @default.
• W2997571627 hasBestOaLocation W29975716271 @default.
• W2997571627 hasConcept C115725540 @default.
• W2997571627 hasConcept C126322002 @default.
• W2997571627 hasConcept C136935669 @default.
• W2997571627 hasConcept C144469398 @default.
• W2997571627 hasConcept C164705383 @default.
• W2997571627 hasConcept C36036425 @default.
• W2997571627 hasConcept C500558357 @default.
• W2997571627 hasConcept C71924100 @default.
• W2997571627 hasConceptScore W2997571627C115725540 @default.
• W2997571627 hasConceptScore W2997571627C126322002 @default.
• W2997571627 hasConceptScore W2997571627C136935669 @default.
• W2997571627 hasConceptScore W2997571627C144469398 @default.
• W2997571627 hasConceptScore W2997571627C164705383 @default.
• W2997571627 hasConceptScore W2997571627C36036425 @default.
• W2997571627 hasConceptScore W2997571627C500558357 @default.
• W2997571627 hasConceptScore W2997571627C71924100 @default.
• W2997571627 hasIssue "1" @default.
• W2997571627 hasLocation W29975716271 @default.
• W2997571627 hasLocation W29975716272 @default.
• W2997571627 hasLocation W29975716273 @default.
• W2997571627 hasLocation W29975716274 @default.
• W2997571627 hasLocation W29975716275 @default.
• W2997571627 hasLocation W29975716276 @default.
• W2997571627 hasLocation W29975716277 @default.
• W2997571627 hasLocation W29975716278 @default.
• W2997571627 hasOpenAccess W2997571627 @default.
• W2997571627 hasPrimaryLocation W29975716271 @default.
• W2997571627 hasRelatedWork W1999689773 @default.
• W2997571627 hasRelatedWork W2006180981 @default.
• W2997571627 hasRelatedWork W2013195452 @default.
• W2997571627 hasRelatedWork W2078151606 @default.
• W2997571627 hasRelatedWork W2379599041 @default.
• W2997571627 hasRelatedWork W2409687048 @default.

• next