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- W2997661662 abstract "Human spaceflight endeavors present an opportunity to expand our presence beyond Earth. To this end, it is crucial to understand and diagnose effects of long-term space travel on the human body. Developing tools for targeted, on-site detection of specific DNA sequences will allow us to establish research and diagnostics platforms that will benefit space programs. We describe a simple DNA diagnostic method that utilizes colorimetric loop-mediated isothermal amplification (LAMP) to enable detection of a repetitive telomeric DNA sequence in as little as 30 minutes. A proof of concept assay for this method was carried out using existing hardware on the International Space Station and the results were read instantly by an astronaut through a simple color change of the reaction mixture. LAMP offers a novel platform for on-orbit DNA-based diagnostics that can be deployed on the International Space Station and to the broader benefit of space programs." @default.
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- W2997661662 date "2020-01-16" @default.
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- W2997661662 title "Nucleic acid detection aboard the International Space Station by colorimetric loop‐mediated isothermal amplification (LAMP)" @default.
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- W2997661662 doi "https://doi.org/10.1096/fba.2019-00088" @default.
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