FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2997737559> ?p ?o ?g. }

• W2997737559 endingPage "1103" @default.
• W2997737559 startingPage "1095" @default.
• W2997737559 abstract "BackgroundThere is area of controversy and variability in the recommendation for the role of adjuvant therapy after R0 resection of a Masaoka stage IIB and III thymic carcinoma. This study investigated the role of adjuvant therapy in patients who had complete surgical resection for thymic carcinoma.MethodsPatients with stage IIB and III thymic carcinoma who underwent curative resection were queried and categorized according to Masaoka-Koga stage groups from the National Cancer Database. Patients were grouped by treatment status (surgery only or surgery followed by adjuvant therapy). Kaplan-Meier estimates of overall survival and univariate and multivariate Cox proportional hazards regression analyses were performed.ResultsFrom 2004 to 2013, 632 surgical patients with stage IIB and III thymic carcinoma were selected for analysis. In stage IIB patients, the adjuvant therapy group had improved survival compared with the surgery only group (P = .01), although no survival difference was observed in patients who had R0 resection between the 2 groups (P = .59). In multivariate analysis, age (P < .001) and grade III and IV (P = .02) negatively impacted survival; the adjuvant therapy improved survival (P < .02). For stage III cancer, the adjuvant therapy group had improved survival compared with the OS group regardless of margin status. In multivariate analysis, tumor size exceeding 70 mm (P = .02) and positive margin (P < .01) negatively affected survival; adjuvant therapy improved survival (P < .01).ConclusionsAdjuvant therapy showed no benefit in patients with stage IIB cancer who had R0 resection. Use of adjuvant therapy should be strongly considered for stage IIB cancer patients with positive margins and all stage III thymic cancer patients. There is area of controversy and variability in the recommendation for the role of adjuvant therapy after R0 resection of a Masaoka stage IIB and III thymic carcinoma. This study investigated the role of adjuvant therapy in patients who had complete surgical resection for thymic carcinoma. Patients with stage IIB and III thymic carcinoma who underwent curative resection were queried and categorized according to Masaoka-Koga stage groups from the National Cancer Database. Patients were grouped by treatment status (surgery only or surgery followed by adjuvant therapy). Kaplan-Meier estimates of overall survival and univariate and multivariate Cox proportional hazards regression analyses were performed. From 2004 to 2013, 632 surgical patients with stage IIB and III thymic carcinoma were selected for analysis. In stage IIB patients, the adjuvant therapy group had improved survival compared with the surgery only group (P = .01), although no survival difference was observed in patients who had R0 resection between the 2 groups (P = .59). In multivariate analysis, age (P < .001) and grade III and IV (P = .02) negatively impacted survival; the adjuvant therapy improved survival (P < .02). For stage III cancer, the adjuvant therapy group had improved survival compared with the OS group regardless of margin status. In multivariate analysis, tumor size exceeding 70 mm (P = .02) and positive margin (P < .01) negatively affected survival; adjuvant therapy improved survival (P < .01). Adjuvant therapy showed no benefit in patients with stage IIB cancer who had R0 resection. Use of adjuvant therapy should be strongly considered for stage IIB cancer patients with positive margins and all stage III thymic cancer patients." @default.
• W2997737559 created "2020-01-10" @default.
• W2997737559 creator A5005668744 @default.
• W2997737559 creator A5066707578 @default.
• W2997737559 creator A5080178929 @default.
• W2997737559 creator A5082574259 @default.
• W2997737559 date "2020-04-01" @default.
• W2997737559 modified "2023-09-23" @default.
• W2997737559 title "The Role of Adjuvant Therapy in Advanced Thymic Carcinoma: A National Cancer Database Analysis" @default.
• W2997737559 cites W1517149977 @default.
• W2997737559 cites W1575178527 @default.
• W2997737559 cites W1964521612 @default.
• W2997737559 cites W1984954256 @default.
• W2997737559 cites W1999948285 @default.
• W2997737559 cites W2004079062 @default.
• W2997737559 cites W2019598670 @default.
• W2997737559 cites W2023967320 @default.
• W2997737559 cites W2129168200 @default.
• W2997737559 cites W2167445450 @default.
• W2997737559 cites W2259303964 @default.
• W2997737559 cites W2439437232 @default.
• W2997737559 cites W2461017424 @default.
• W2997737559 cites W2549910402 @default.
• W2997737559 cites W2580626787 @default.
• W2997737559 cites W2599107728 @default.
• W2997737559 doi "https://doi.org/10.1016/j.athoracsur.2019.11.009" @default.
• W2997737559 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31877285" @default.
• W2997737559 hasPublicationYear "2020" @default.
• W2997737559 type Work @default.
• W2997737559 sameAs 2997737559 @default.
• W2997737559 citedByCount "14" @default.
• W2997737559 countsByYear W29977375592020 @default.
• W2997737559 countsByYear W29977375592021 @default.
• W2997737559 countsByYear W29977375592022 @default.
• W2997737559 countsByYear W29977375592023 @default.
• W2997737559 crossrefType "journal-article" @default.
• W2997737559 hasAuthorship W2997737559A5005668744 @default.
• W2997737559 hasAuthorship W2997737559A5066707578 @default.
• W2997737559 hasAuthorship W2997737559A5080178929 @default.
• W2997737559 hasAuthorship W2997737559A5082574259 @default.
• W2997737559 hasBestOaLocation W29977375591 @default.
• W2997737559 hasConcept C10515644 @default.
• W2997737559 hasConcept C121608353 @default.
• W2997737559 hasConcept C126322002 @default.
• W2997737559 hasConcept C141071460 @default.
• W2997737559 hasConcept C143998085 @default.
• W2997737559 hasConcept C144301174 @default.
• W2997737559 hasConcept C146357865 @default.
• W2997737559 hasConcept C151730666 @default.
• W2997737559 hasConcept C159110652 @default.
• W2997737559 hasConcept C2776349617 @default.
• W2997737559 hasConcept C2776694085 @default.
• W2997737559 hasConcept C2777546739 @default.
• W2997737559 hasConcept C2777863537 @default.
• W2997737559 hasConcept C2777982462 @default.
• W2997737559 hasConcept C2778132481 @default.
• W2997737559 hasConcept C2778913397 @default.
• W2997737559 hasConcept C38180746 @default.
• W2997737559 hasConcept C50382708 @default.
• W2997737559 hasConcept C71924100 @default.
• W2997737559 hasConcept C86803240 @default.
• W2997737559 hasConceptScore W2997737559C10515644 @default.
• W2997737559 hasConceptScore W2997737559C121608353 @default.
• W2997737559 hasConceptScore W2997737559C126322002 @default.
• W2997737559 hasConceptScore W2997737559C141071460 @default.
• W2997737559 hasConceptScore W2997737559C143998085 @default.
• W2997737559 hasConceptScore W2997737559C144301174 @default.
• W2997737559 hasConceptScore W2997737559C146357865 @default.
• W2997737559 hasConceptScore W2997737559C151730666 @default.
• W2997737559 hasConceptScore W2997737559C159110652 @default.
• W2997737559 hasConceptScore W2997737559C2776349617 @default.
• W2997737559 hasConceptScore W2997737559C2776694085 @default.
• W2997737559 hasConceptScore W2997737559C2777546739 @default.
• W2997737559 hasConceptScore W2997737559C2777863537 @default.
• W2997737559 hasConceptScore W2997737559C2777982462 @default.
• W2997737559 hasConceptScore W2997737559C2778132481 @default.
• W2997737559 hasConceptScore W2997737559C2778913397 @default.
• W2997737559 hasConceptScore W2997737559C38180746 @default.
• W2997737559 hasConceptScore W2997737559C50382708 @default.
• W2997737559 hasConceptScore W2997737559C71924100 @default.
• W2997737559 hasConceptScore W2997737559C86803240 @default.
• W2997737559 hasIssue "4" @default.
• W2997737559 hasLocation W29977375591 @default.
• W2997737559 hasLocation W29977375592 @default.
• W2997737559 hasOpenAccess W2997737559 @default.
• W2997737559 hasPrimaryLocation W29977375591 @default.
• W2997737559 hasRelatedWork W1987677298 @default.
• W2997737559 hasRelatedWork W2046399375 @default.
• W2997737559 hasRelatedWork W2361700749 @default.
• W2997737559 hasRelatedWork W2375628929 @default.
• W2997737559 hasRelatedWork W2386134303 @default.
• W2997737559 hasRelatedWork W2405817813 @default.
• W2997737559 hasRelatedWork W2411442805 @default.
• W2997737559 hasRelatedWork W2616212697 @default.
• W2997737559 hasRelatedWork W3208622157 @default.
• W2997737559 hasRelatedWork W4206735833 @default.
• W2997737559 hasVolume "109" @default.
• W2997737559 isParatext "false" @default.

• next