FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2998049327> ?p ?o ?g. }

• W2998049327 abstract "Lipoprotein-associated phospholipase A2 (Lp-PLA2) and high-sensitivity C-reactive protein (hs-CRP) have been reported to be associated with cardiovascular disease (CVD). However, whether the combination of these two markers can improve the prediction of CVD is unknown.A total of 1,921 participants without CVD, aged 40 years or older, were enrolled from 2010 to 2011. Plasma Lp-PLA2 and hs-CRP were measured at baseline. Participants were subsequently followed until December 2015. We identified a total of 148 cardiovascular events (myocardial infarction, stroke, and all-cause death). Cox proportional-hazard models were used to determine the association between two independent markers and cardiovascular outcomes. The C statistic, Net Reclassification Improvement (NRI), and Integrated Discrimination Improvement (IDI) were used to determine the utility of the two markers in predicting cardiovascular risk.After adjustment for potential confounders, compared with the first quartile, hazard ratios (HRs) with 95% confidence interval (CI) for the third and fourth quartiles for Lp-PLA2 were 2.09 (1.17-3.73) and 2.62 (1.48-4.67), respectively, and HRs with 95%CI for the fourth quartile for hs-CRP was 1.78 (1.08-4.67). Compared with conventional risk factors, the combination of hs-CRP and Lp-PLA2 provided greater incremental information, and the C statistic increased by 0.013. The NRI and IDI were also statistically significant for cardiovascular events (P = 0.004 and P < 0.001, respectively).Hs-CRP and Lp-PLA2 have complementary effects in predicting cardiovascular outcomes in adults aged 40 years or older." @default.
• W2998049327 created "2020-01-10" @default.
• W2998049327 creator A5015184109 @default.
• W2998049327 creator A5020200362 @default.
• W2998049327 creator A5031066775 @default.
• W2998049327 creator A5033425658 @default.
• W2998049327 creator A5049927017 @default.
• W2998049327 creator A5075446655 @default.
• W2998049327 date "2020-01-31" @default.
• W2998049327 modified "2023-10-17" @default.
• W2998049327 title "Biomarkers for Prediction of Cardiovascular Events in Community-Dwelling Adults Aged 40 or Older" @default.
• W2998049327 cites W1520348292 @default.
• W2998049327 cites W1986113484 @default.
• W2998049327 cites W1987709455 @default.
• W2998049327 cites W2005841342 @default.
• W2998049327 cites W2020150044 @default.
• W2998049327 cites W2030076560 @default.
• W2998049327 cites W2030469973 @default.
• W2998049327 cites W2030522545 @default.
• W2998049327 cites W2032295615 @default.
• W2998049327 cites W2039244298 @default.
• W2998049327 cites W2063274643 @default.
• W2998049327 cites W2109582930 @default.
• W2998049327 cites W2112316706 @default.
• W2998049327 cites W2126830306 @default.
• W2998049327 cites W2131261486 @default.
• W2998049327 cites W2133593325 @default.
• W2998049327 cites W2145689683 @default.
• W2998049327 cites W2167266057 @default.
• W2998049327 cites W2253359374 @default.
• W2998049327 cites W2410892427 @default.
• W2998049327 cites W2523430175 @default.
• W2998049327 cites W2534148248 @default.
• W2998049327 cites W2546624117 @default.
• W2998049327 cites W2560549015 @default.
• W2998049327 cites W2604638361 @default.
• W2998049327 cites W2614708982 @default.
• W2998049327 cites W2746981989 @default.
• W2998049327 cites W2769178920 @default.
• W2998049327 cites W2778149363 @default.
• W2998049327 cites W2790722578 @default.
• W2998049327 cites W2792996915 @default.
• W2998049327 cites W2794101207 @default.
• W2998049327 cites W2884114539 @default.
• W2998049327 cites W2888778477 @default.
• W2998049327 cites W2912795838 @default.
• W2998049327 doi "https://doi.org/10.1536/ihj.19-240" @default.
• W2998049327 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31875617" @default.
• W2998049327 hasPublicationYear "2020" @default.
• W2998049327 type Work @default.
• W2998049327 sameAs 2998049327 @default.
• W2998049327 citedByCount "2" @default.
• W2998049327 countsByYear W29980493272022 @default.
• W2998049327 crossrefType "journal-article" @default.
• W2998049327 hasAuthorship W2998049327A5015184109 @default.
• W2998049327 hasAuthorship W2998049327A5020200362 @default.
• W2998049327 hasAuthorship W2998049327A5031066775 @default.
• W2998049327 hasAuthorship W2998049327A5033425658 @default.
• W2998049327 hasAuthorship W2998049327A5049927017 @default.
• W2998049327 hasAuthorship W2998049327A5075446655 @default.
• W2998049327 hasBestOaLocation W29980493271 @default.
• W2998049327 hasConcept C126322002 @default.
• W2998049327 hasConcept C127413603 @default.
• W2998049327 hasConcept C164705383 @default.
• W2998049327 hasConcept C207103383 @default.
• W2998049327 hasConcept C2776914184 @default.
• W2998049327 hasConcept C2777034527 @default.
• W2998049327 hasConcept C2778163477 @default.
• W2998049327 hasConcept C2780072125 @default.
• W2998049327 hasConcept C2780645631 @default.
• W2998049327 hasConcept C2781195455 @default.
• W2998049327 hasConcept C44249647 @default.
• W2998049327 hasConcept C500558357 @default.
• W2998049327 hasConcept C50382708 @default.
• W2998049327 hasConcept C68443243 @default.
• W2998049327 hasConcept C71924100 @default.
• W2998049327 hasConcept C77350462 @default.
• W2998049327 hasConcept C78519656 @default.
• W2998049327 hasConceptScore W2998049327C126322002 @default.
• W2998049327 hasConceptScore W2998049327C127413603 @default.
• W2998049327 hasConceptScore W2998049327C164705383 @default.
• W2998049327 hasConceptScore W2998049327C207103383 @default.
• W2998049327 hasConceptScore W2998049327C2776914184 @default.
• W2998049327 hasConceptScore W2998049327C2777034527 @default.
• W2998049327 hasConceptScore W2998049327C2778163477 @default.
• W2998049327 hasConceptScore W2998049327C2780072125 @default.
• W2998049327 hasConceptScore W2998049327C2780645631 @default.
• W2998049327 hasConceptScore W2998049327C2781195455 @default.
• W2998049327 hasConceptScore W2998049327C44249647 @default.
• W2998049327 hasConceptScore W2998049327C500558357 @default.
• W2998049327 hasConceptScore W2998049327C50382708 @default.
• W2998049327 hasConceptScore W2998049327C68443243 @default.
• W2998049327 hasConceptScore W2998049327C71924100 @default.
• W2998049327 hasConceptScore W2998049327C77350462 @default.
• W2998049327 hasConceptScore W2998049327C78519656 @default.
• W2998049327 hasLocation W29980493271 @default.
• W2998049327 hasLocation W29980493272 @default.
• W2998049327 hasOpenAccess W2998049327 @default.
• W2998049327 hasPrimaryLocation W29980493271 @default.
• W2998049327 hasRelatedWork W1238589527 @default.

• next