Matches in SemOpenAlex for { <https://semopenalex.org/work/W2998166654> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2998166654 endingPage "S715" @default.
- W2998166654 startingPage "S715" @default.
- W2998166654 abstract "Preeclampsia (PE) is a pregnancy specific vascular endothelial disorder that involves an imbalance in the biosynthesis of two eicosanoids, thromboxane A2 (vasoconstrictor) and prostacyclin (vasodilator). PE is characterized by multi-organ system involvement, including maternal renal involvement, such as continuous vasospasm of renal arteries and reduced renal blood flow. However, it is unclear whether similar renal vascular changes are seen in the fetus. This study sought to compare renal artery impedance in fetuses of women with and without PE. This was a prospective Doppler assessment study of the fetal renal artery impedance in 48 singleton fetuses. The group with PE consisted of 24 appropriately grown fetuses in pregnancies complicated by both mild and severe preeclampsia, and the control group consisted of 24 uncomplicated pregnancies. Doppler studies included renal artery systolic/diastolic (S/D) ratio, pulsatility index (PI), resistance index (RI), and identification of end-diastolic blood flow. Student's t-test, Mann-Whitney U and chi-squared tests were used as indicated. Images were obtained on a Samsung WS80-A device using a 1-7MHz transducer (Figure 1). Maternal age (28.9 ±6.1 vs 29.3 ±5.8, p=0.85), race (p=0.81), gestational age at enrollment (31 [29-33] vs 32 [31-33] weeks’ gestation, p=0.155), and birthweight (1655 ±608 vs 2008 ±567, p=0.10) were similar between study and control groups. Fetuses of mothers with PE were more likely to have a lower renal artery Doppler S/D ratio (7.85 [6.4-10.2] vs 10.8 [7.75-22.5], p=0.03) and lower resistance index (0.875 [0.842-0.898] vs 0.905 [0.872-0.957], p=0.03). However, there was no statistically significant difference in pulsatility index or the incidence of absent end-diastolic flow. This study suggests that PE results in changes in blood flow to the renal arteries of the fetus. The apparent reduction in resistance in fetal renal arteries may be related to a significant increase in prostacyclin in the fetal circulation in PE – an effect that is less seen in the maternal circulation." @default.
- W2998166654 created "2020-01-10" @default.
- W2998166654 creator A5017463287 @default.
- W2998166654 creator A5038053256 @default.
- W2998166654 creator A5040827809 @default.
- W2998166654 creator A5045724266 @default.
- W2998166654 creator A5090114484 @default.
- W2998166654 date "2020-01-01" @default.
- W2998166654 modified "2023-10-17" @default.
- W2998166654 title "1162: Fetal renal artery impedance in pregnancies affected by preeclampsia" @default.
- W2998166654 doi "https://doi.org/10.1016/j.ajog.2019.11.1174" @default.
- W2998166654 hasPublicationYear "2020" @default.
- W2998166654 type Work @default.
- W2998166654 sameAs 2998166654 @default.
- W2998166654 citedByCount "0" @default.
- W2998166654 crossrefType "journal-article" @default.
- W2998166654 hasAuthorship W2998166654A5017463287 @default.
- W2998166654 hasAuthorship W2998166654A5038053256 @default.
- W2998166654 hasAuthorship W2998166654A5040827809 @default.
- W2998166654 hasAuthorship W2998166654A5045724266 @default.
- W2998166654 hasAuthorship W2998166654A5090114484 @default.
- W2998166654 hasBestOaLocation W29981666541 @default.
- W2998166654 hasConcept C126322002 @default.
- W2998166654 hasConcept C131872663 @default.
- W2998166654 hasConcept C142225936 @default.
- W2998166654 hasConcept C164705383 @default.
- W2998166654 hasConcept C172680121 @default.
- W2998166654 hasConcept C178853913 @default.
- W2998166654 hasConcept C2776634560 @default.
- W2998166654 hasConcept C2777218350 @default.
- W2998166654 hasConcept C2778376644 @default.
- W2998166654 hasConcept C2779234561 @default.
- W2998166654 hasConcept C2780091579 @default.
- W2998166654 hasConcept C46973012 @default.
- W2998166654 hasConcept C54355233 @default.
- W2998166654 hasConcept C58245268 @default.
- W2998166654 hasConcept C71924100 @default.
- W2998166654 hasConcept C86803240 @default.
- W2998166654 hasConceptScore W2998166654C126322002 @default.
- W2998166654 hasConceptScore W2998166654C131872663 @default.
- W2998166654 hasConceptScore W2998166654C142225936 @default.
- W2998166654 hasConceptScore W2998166654C164705383 @default.
- W2998166654 hasConceptScore W2998166654C172680121 @default.
- W2998166654 hasConceptScore W2998166654C178853913 @default.
- W2998166654 hasConceptScore W2998166654C2776634560 @default.
- W2998166654 hasConceptScore W2998166654C2777218350 @default.
- W2998166654 hasConceptScore W2998166654C2778376644 @default.
- W2998166654 hasConceptScore W2998166654C2779234561 @default.
- W2998166654 hasConceptScore W2998166654C2780091579 @default.
- W2998166654 hasConceptScore W2998166654C46973012 @default.
- W2998166654 hasConceptScore W2998166654C54355233 @default.
- W2998166654 hasConceptScore W2998166654C58245268 @default.
- W2998166654 hasConceptScore W2998166654C71924100 @default.
- W2998166654 hasConceptScore W2998166654C86803240 @default.
- W2998166654 hasIssue "1" @default.
- W2998166654 hasLocation W29981666541 @default.
- W2998166654 hasOpenAccess W2998166654 @default.
- W2998166654 hasPrimaryLocation W29981666541 @default.
- W2998166654 hasRelatedWork W1995255121 @default.
- W2998166654 hasRelatedWork W1999003732 @default.
- W2998166654 hasRelatedWork W2052494798 @default.
- W2998166654 hasRelatedWork W2059300309 @default.
- W2998166654 hasRelatedWork W2082713613 @default.
- W2998166654 hasRelatedWork W2093841670 @default.
- W2998166654 hasRelatedWork W2333891256 @default.
- W2998166654 hasRelatedWork W2522999477 @default.
- W2998166654 hasRelatedWork W2906386199 @default.
- W2998166654 hasRelatedWork W4224607730 @default.
- W2998166654 hasVolume "222" @default.
- W2998166654 isParatext "false" @default.
- W2998166654 isRetracted "false" @default.
- W2998166654 magId "2998166654" @default.
- W2998166654 workType "article" @default.