FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2998378082> ?p ?o ?g. }

• W2998378082 endingPage "325" @default.
• W2998378082 startingPage "317" @default.
• W2998378082 abstract "BACKGROUND Transfusion‐transmitted Babesia microti is well recognized in the Northeast and upper Midwestern United States. Blood donation screening in Babesia ‐endemic states has occurred under investigational protocols prior to US Food and Drug Administration–licensed test availability. Here, we provide a prospective screening summary of nucleic acid testing (NAT) as part of a multicenter Babesia pivotal trial followed by extended investigational use. METHODS From June 2017 to February 2018, 176,928 donation samples were tested with Procleix Babesia Assay (Grifols Diagnostic Solutions), a blood screening NAT for Babesia species ribosomal RNA detection using whole blood samples. During the pivotal trial, donations were collected in 11 endemic states plus Washington, DC, and Florida (nonendemic). Whole blood lysate samples were either tested in pools of 16 or individually. Reactive samples were confirmed by Babesia microti antibody and polymerase chain reaction (PCR) testing. If unconfirmed, further testing used a second PCR assay capable of detecting multiple Babesia species. Follow‐up samples were also tested. Extended investigational testing followed pivotal trial completion. RESULTS The pivotal trial identified 61 confirmed positives (176,608 donations): 35 (57%) PCR positive, 59 (97%) antibody positive, and two (3%) NAT positive/antibody negative, for a total yield of one positive per 2895 donations, including one Florida resident; others were from seven endemic states. During extended investigational testing of 496,270 donations in endemic states through January 2019, 211 (1:2351) repeat reactive donations were identified. CONCLUSIONS Babesia was detected in donors from multiple US states, including one previously not associated with positive blood donors. This study supports the use of the Procleix Babesia Assay using individual testing or pools of up to 16." @default.
• W2998378082 created "2020-01-10" @default.
• W2998378082 creator A5001164366 @default.
• W2998378082 creator A5003423078 @default.
• W2998378082 creator A5013639498 @default.
• W2998378082 creator A5031629327 @default.
• W2998378082 creator A5033129438 @default.
• W2998378082 creator A5039444837 @default.
• W2998378082 creator A5060105183 @default.
• W2998378082 creator A5062975649 @default.
• W2998378082 creator A5065929925 @default.
• W2998378082 creator A5066583392 @default.
• W2998378082 creator A5072397925 @default.
• W2998378082 creator A5074410718 @default.
• W2998378082 creator A5081391652 @default.
• W2998378082 creator A5089721094 @default.
• W2998378082 date "2019-12-29" @default.
• W2998378082 modified "2023-10-14" @default.
• W2998378082 title "Transcription‐mediated amplification blood donation screening for <i>Babesia</i>" @default.
• W2998378082 cites W1494507349 @default.
• W2998378082 cites W1501520701 @default.
• W2998378082 cites W1558877703 @default.
• W2998378082 cites W1797635378 @default.
• W2998378082 cites W1964221725 @default.
• W2998378082 cites W1983910626 @default.
• W2998378082 cites W2017126361 @default.
• W2998378082 cites W2017667551 @default.
• W2998378082 cites W2117137797 @default.
• W2998378082 cites W2117367522 @default.
• W2998378082 cites W2152658642 @default.
• W2998378082 cites W2170848108 @default.
• W2998378082 cites W2261853667 @default.
• W2998378082 cites W2313625964 @default.
• W2998378082 cites W2342056110 @default.
• W2998378082 cites W2517174901 @default.
• W2998378082 cites W2560808412 @default.
• W2998378082 cites W2596550671 @default.
• W2998378082 cites W2699752581 @default.
• W2998378082 cites W2742207338 @default.
• W2998378082 cites W2792996223 @default.
• W2998378082 cites W2802296577 @default.
• W2998378082 cites W2894153313 @default.
• W2998378082 cites W2902015084 @default.
• W2998378082 cites W2913948882 @default.
• W2998378082 cites W2948019596 @default.
• W2998378082 cites W2954813303 @default.
• W2998378082 cites W4211025802 @default.
• W2998378082 cites W4248804859 @default.
• W2998378082 doi "https://doi.org/10.1111/trf.15630" @default.
• W2998378082 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31885102" @default.
• W2998378082 hasPublicationYear "2019" @default.
• W2998378082 type Work @default.
• W2998378082 sameAs 2998378082 @default.
• W2998378082 citedByCount "15" @default.
• W2998378082 countsByYear W29983780822020 @default.
• W2998378082 countsByYear W29983780822021 @default.
• W2998378082 countsByYear W29983780822022 @default.
• W2998378082 countsByYear W29983780822023 @default.
• W2998378082 crossrefType "journal-article" @default.
• W2998378082 hasAuthorship W2998378082A5001164366 @default.
• W2998378082 hasAuthorship W2998378082A5003423078 @default.
• W2998378082 hasAuthorship W2998378082A5013639498 @default.
• W2998378082 hasAuthorship W2998378082A5031629327 @default.
• W2998378082 hasAuthorship W2998378082A5033129438 @default.
• W2998378082 hasAuthorship W2998378082A5039444837 @default.
• W2998378082 hasAuthorship W2998378082A5060105183 @default.
• W2998378082 hasAuthorship W2998378082A5062975649 @default.
• W2998378082 hasAuthorship W2998378082A5065929925 @default.
• W2998378082 hasAuthorship W2998378082A5066583392 @default.
• W2998378082 hasAuthorship W2998378082A5072397925 @default.
• W2998378082 hasAuthorship W2998378082A5074410718 @default.
• W2998378082 hasAuthorship W2998378082A5081391652 @default.
• W2998378082 hasAuthorship W2998378082A5089721094 @default.
• W2998378082 hasConcept C126322002 @default.
• W2998378082 hasConcept C159047783 @default.
• W2998378082 hasConcept C1621761 @default.
• W2998378082 hasConcept C2778145968 @default.
• W2998378082 hasConcept C2780014101 @default.
• W2998378082 hasConcept C2780581805 @default.
• W2998378082 hasConcept C2908668021 @default.
• W2998378082 hasConcept C71924100 @default.
• W2998378082 hasConcept C86803240 @default.
• W2998378082 hasConceptScore W2998378082C126322002 @default.
• W2998378082 hasConceptScore W2998378082C159047783 @default.
• W2998378082 hasConceptScore W2998378082C1621761 @default.
• W2998378082 hasConceptScore W2998378082C2778145968 @default.
• W2998378082 hasConceptScore W2998378082C2780014101 @default.
• W2998378082 hasConceptScore W2998378082C2780581805 @default.
• W2998378082 hasConceptScore W2998378082C2908668021 @default.
• W2998378082 hasConceptScore W2998378082C71924100 @default.
• W2998378082 hasConceptScore W2998378082C86803240 @default.
• W2998378082 hasIssue "2" @default.
• W2998378082 hasLocation W29983780821 @default.
• W2998378082 hasLocation W29983780822 @default.
• W2998378082 hasOpenAccess W2998378082 @default.
• W2998378082 hasPrimaryLocation W29983780821 @default.
• W2998378082 hasRelatedWork W1988571581 @default.
• W2998378082 hasRelatedWork W2047281902 @default.

• next