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• W2998529439 startingPage "183" @default.
• W2998529439 abstract "Development of multicellular organisms requires coordination of cell division and differentiation across tissues. In plants, directional signaling, and implicitly cell polarity, is proposed to participate in this coordination; however, mechanistic links between intercellular signaling, cell polarity, and cellular organization remain unclear. Here, we investigate the localization and function of INFLORESCENCE AND ROOT APICES RECEPTOR KINASE (IRK) in root development. We find that IRK-GFP localizes to the outer plasma membrane domain in endodermal cells but localizes to different domains in other cell types. Our results suggest that IRK localization is informed locally by adjacent cell types. irk mutants have excess cell divisions in the ground tissue stem cells and endodermis, indicating IRK functions to maintain tissue organization through inhibition of specific cell divisions. We predict that IRK perceives a directional cue that negatively regulates these cell divisions, thus linking intercellular signaling and cell polarity with the control of oriented cell divisions during development." @default.
• W2998529439 created "2020-01-10" @default.
• W2998529439 creator A5016301912 @default.
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• W2998529439 creator A5033829285 @default.
• W2998529439 creator A5037397735 @default.
• W2998529439 date "2020-01-01" @default.
• W2998529439 modified "2023-10-14" @default.
• W2998529439 title "The Arabidopsis Receptor Kinase IRK Is Polarized and Represses Specific Cell Divisions in Roots" @default.
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• W2998529439 doi "https://doi.org/10.1016/j.devcel.2019.12.001" @default.
• W2998529439 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31883775" @default.
• W2998529439 hasPublicationYear "2020" @default.
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