Matches in SemOpenAlex for { <https://semopenalex.org/work/W2998535038> ?p ?o ?g. }
- W2998535038 endingPage "296" @default.
- W2998535038 startingPage "296" @default.
- W2998535038 abstract "Gender medicine is the first step of personalized medicine and patient-centred care, an essential development to achieve the standard goal of a holistic approach to patients and diseases. By addressing the interrelation and integration of biological markers (i.e., sex) with indicators of psychological/cultural behaviour (i.e., gender), gender medicine represents the crucial assumption for achieving the personalized health-care required in the third millennium. However, ‘sex’ and ‘gender’ are often misused as synonyms, leading to frequent misunderstandings in those who are not deeply involved in the field. Overall, we have to face the evidence that biological, genetic, epigenetic, psycho-social, cultural, and environmental factors mutually interact in defining sex/gender differences, and at the same time in establishing potential unwanted sex/gender disparities. Prioritizing the role of sex/gender in physiological and pathological processes is crucial in terms of efficient prevention, clinical signs’ identification, prognosis definition, and therapy optimization. In this regard, the omics-approach has become a powerful tool to identify sex/gender-specific disease markers, with potential benefits also in terms of socio-psychological wellbeing for each individual, and cost-effectiveness for National Healthcare systems. “Being a male or being a female” is indeed important from a health point of view and it is no longer possible to avoid “sex and gender lens” when approaching patients. Accordingly, personalized healthcare must be based on evidence from targeted research studies aimed at understanding how sex and gender influence health across the entire life span. The rapid development of genetic tools in the molecular medicine approaches and their impact in healthcare is an example of highly specialized applications that have moved from specialists to primary care providers (e.g., pharmacogenetic and pharmacogenomic applications in routine medical practice). Gender medicine needs to follow the same path and become an established medical approach. To face the genetic, molecular and pharmacological bases of the existing sex/gender gap by means of omics approaches will pave the way to the discovery and identification of novel drug-targets/therapeutic protocols, personalized laboratory tests and diagnostic procedures (sex/gender-omics). In this scenario, the aim of the present review is not to simply resume the state-of-the-art in the field, rather an opportunity to gain insights into gender medicine, spanning from molecular up to social and psychological stances. The description and critical discussion of some key selected multidisciplinary topics considered as paradigmatic of sex/gender differences and sex/gender inequalities will allow to draft and design strategies useful to fill the existing gap and move forward." @default.
- W2998535038 created "2020-01-10" @default.
- W2998535038 creator A5001521177 @default.
- W2998535038 creator A5013758426 @default.
- W2998535038 creator A5027329662 @default.
- W2998535038 creator A5030471925 @default.
- W2998535038 creator A5050386316 @default.
- W2998535038 creator A5074592517 @default.
- W2998535038 creator A5080279246 @default.
- W2998535038 creator A5082312639 @default.
- W2998535038 creator A5084314174 @default.
- W2998535038 creator A5091130945 @default.
- W2998535038 date "2019-12-31" @default.
- W2998535038 modified "2023-10-05" @default.
- W2998535038 title "“Bridging the Gap” Everything that Could Have Been Avoided If We Had Applied Gender Medicine, Pharmacogenetics and Personalized Medicine in the Gender-Omics and Sex-Omics Era" @default.
- W2998535038 cites W108801881 @default.
- W2998535038 cites W1504221074 @default.
- W2998535038 cites W1520497097 @default.
- W2998535038 cites W1557360794 @default.
- W2998535038 cites W1593684700 @default.
- W2998535038 cites W1598838718 @default.
- W2998535038 cites W1603901790 @default.
- W2998535038 cites W1679888031 @default.
- W2998535038 cites W1749634143 @default.
- W2998535038 cites W1772243494 @default.
- W2998535038 cites W1833247476 @default.
- W2998535038 cites W1898738856 @default.
- W2998535038 cites W1964792919 @default.
- W2998535038 cites W1965401478 @default.
- W2998535038 cites W1966397423 @default.
- W2998535038 cites W1966694479 @default.
- W2998535038 cites W1966977570 @default.
- W2998535038 cites W1970140452 @default.
- W2998535038 cites W1970937149 @default.
- W2998535038 cites W1971598476 @default.
- W2998535038 cites W1975592609 @default.
- W2998535038 cites W1976256751 @default.
- W2998535038 cites W1982569141 @default.
- W2998535038 cites W1984737558 @default.
- W2998535038 cites W1984896511 @default.
- W2998535038 cites W1987700102 @default.
- W2998535038 cites W1991708590 @default.
- W2998535038 cites W1992368595 @default.
- W2998535038 cites W1992841863 @default.
- W2998535038 cites W2000492372 @default.
- W2998535038 cites W2000802353 @default.
- W2998535038 cites W2000836755 @default.
- W2998535038 cites W2001636656 @default.
- W2998535038 cites W2004001621 @default.
- W2998535038 cites W2005022514 @default.
- W2998535038 cites W2006420315 @default.
- W2998535038 cites W2006582030 @default.
- W2998535038 cites W2007703345 @default.
- W2998535038 cites W2008778245 @default.
- W2998535038 cites W2011462820 @default.
- W2998535038 cites W2011861966 @default.
- W2998535038 cites W2013909104 @default.
- W2998535038 cites W2014214431 @default.
- W2998535038 cites W2014480218 @default.
- W2998535038 cites W2015672115 @default.
- W2998535038 cites W2018818620 @default.
- W2998535038 cites W2019242459 @default.
- W2998535038 cites W2020359138 @default.
- W2998535038 cites W2020958409 @default.
- W2998535038 cites W2021411451 @default.
- W2998535038 cites W2021767615 @default.
- W2998535038 cites W2027163659 @default.
- W2998535038 cites W2027431314 @default.
- W2998535038 cites W2029225735 @default.
- W2998535038 cites W2030605465 @default.
- W2998535038 cites W2030627876 @default.
- W2998535038 cites W2031050297 @default.
- W2998535038 cites W2038054049 @default.
- W2998535038 cites W2038682678 @default.
- W2998535038 cites W2040287039 @default.
- W2998535038 cites W2042445733 @default.
- W2998535038 cites W2042701594 @default.
- W2998535038 cites W2044687155 @default.
- W2998535038 cites W2044984283 @default.
- W2998535038 cites W2045301131 @default.
- W2998535038 cites W2045688706 @default.
- W2998535038 cites W2045902115 @default.
- W2998535038 cites W2049512200 @default.
- W2998535038 cites W2052317102 @default.
- W2998535038 cites W2054153086 @default.
- W2998535038 cites W2054868893 @default.
- W2998535038 cites W2055171044 @default.
- W2998535038 cites W2055606086 @default.
- W2998535038 cites W2058988237 @default.
- W2998535038 cites W2059300128 @default.
- W2998535038 cites W2060188978 @default.
- W2998535038 cites W2062283207 @default.
- W2998535038 cites W2065220212 @default.
- W2998535038 cites W2066468959 @default.
- W2998535038 cites W2069764798 @default.
- W2998535038 cites W2070495303 @default.
- W2998535038 cites W2072662024 @default.
- W2998535038 cites W2074772870 @default.