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- W299875771 abstract "MicroRNAs (miRNAs), which are small single-stranded RNA molecules composed of 18-23 nucleotides, act as oncogenes or tumor suppressor genes playing important roles in tumor formation, infiltration and metastasis. Subsequently, miRNAs expression contributes to cancer diagnosis and prognosis. Gastric cancer currently has high morbidity and mortality among all malignant tumors, yet it lacks early specific diagnostic markers and effective treatments. In gastric cancer, many studies have detected abnormal expression forms of miRNAs and confirmed their involvement in its tumorigenesis, progression, invasion and metastasis. They may become valuable diagnostic markers and therapeutic targets for gastric cancer. Studying the role of miRNAs in gastric cancer and its relationship with diagnostic and prognostic parameters might help to improve the sensitivity of diagnosis as well as the efficacy of gastric cancer treatment. This review aims to highlight the advancements which might provide new methods for early clinical diagnosis and effective therapeutic options, along with predict response to treatment for gastric cancer." @default.
- W299875771 created "2016-06-24" @default.
- W299875771 creator A5059406058 @default.
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- W299875771 creator A5074625537 @default.
- W299875771 creator A5081515918 @default.
- W299875771 date "2015-05-22" @default.
- W299875771 modified "2023-10-06" @default.
- W299875771 title "MicroRNAs in tumorigenesis, metastasis, diagnosis and prognosis of gastric cancer" @default.
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