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• W2998910936 abstract "Abstract Background There has been limited longitudinal assessment of the relationship between moderate‐to‐vigorous physical activity (MVPA) and sedentary behaviour (SB) with frailty, and no studies have explored the possibility of reverse causality. This study aimed to determine the potential bidirectionality of the relationship between accelerometer‐assessed MVPA, SB, and frailty over time in older adults. Methods Participants were from the Toledo Study for Healthy Aging. We analysed 186 older people aged 67 to 90 (76.7 ± 3.9; 52.7% female participants) over a 4‐year period. Time spent in SB and MVPA was assessed by accelerometry. Frailty Trait Scale was used to determine frailty levels. A cross‐lagged panel model design was used to test the reciprocal relationships between MVPA/SB and frailty. Results Frailty Trait Scale score changed from 35.4 to 43.8 points between the two times ( P < 0.05). We also found a reduction of 7 min/day in the time spent on MVPA ( P < 0.05), and participants tended to spend more time on SB ( P = 0.076). Our analyses revealed that lower levels of initial MVPA predicted higher levels of later frailty [std. β = −0.126; confidence interval (CI) = −0.231, −0.021; P < 0.05], whereas initial spent time on SB did not predict later frailty (std. β = −0.049; CI = −0.185, 0.087; P = 0.48). Conversely, an initial increased frailty status predicted higher levels of later SB (std. β = 0.167; CI = 0.026, 0.307; P < 0.05) but not those of MVPA (std. β = 0.071; CI = −0.033, 0.175; P = 0.18). Conclusions Our observations suggest that the relationship between MVPA/SB and frailty is unidirectional: individuals who spent less time on MVPA at baseline are more likely to increase their frailty score, and individuals who are more frail are more likely to spent more time on SB at follow‐up. Interventions and policies should aim to increase MVPA levels from earlier stages to promote successful aging." @default.
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• W2998910936 date "2020-01-08" @default.
• W2998910936 modified "2023-10-17" @default.
• W2998910936 title "Which one came first: movement behavior or frailty? A cross‐lagged panel model in the Toledo Study for Healthy Aging" @default.
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• W2998910936 doi "https://doi.org/10.1002/jcsm.12511" @default.
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