FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2998989292> ?p ?o ?g. }

• W2998989292 endingPage "97" @default.
• W2998989292 startingPage "92" @default.
• W2998989292 abstract "Pseudoxanthoma elasticum (PXE; OMIM 264800) is an inherited multisystem disorder associated with accumulation of mineralized and fragmented elastic fibers in the skin, vascular walls, and brush membrane in the eye. Carriers exhibit characteristic lesions in the cardiovascular system, and peripheral and coronary arterial disease as well as mitral valvulopathy often present as a cardiovascular feature of this disease. PXE and chronic kidney disease (CKD) share some common patterns in the vascular damage and in therapeutic approaches as well.To date, treating PXE has focused more on careful follow-up examinations with retinal specialists and cardiologist, avoiding long-term anticoagulation. Like CKD, maintaining a low-calcium diet, increasing dietary magnesium, and administering phosphate binders such as aluminum hydroxide or sevelamer may yield a modest benefit. Recently, 4-phenylbutyrate acid (4-PBA) has demonstrated a maturation of ABCC6 mutant effects into the plasma membrane. Moreover, in a humanized mouse model of PXE, 4-PBA administration restored the physiological function of ABCC6 mutants, resulting in enhanced calcification inhibition and thus a promising strategy for allele-specific therapy of ABCC6-associated calcification disorders.Vascular compromise in PXE patients share some components similar to CKD." @default.
• W2998989292 created "2020-01-23" @default.
• W2998989292 creator A5021622992 @default.
• W2998989292 creator A5061319183 @default.
• W2998989292 creator A5075780633 @default.
• W2998989292 creator A5087105111 @default.
• W2998989292 creator A5090919713 @default.
• W2998989292 date "2020-01-01" @default.
• W2998989292 modified "2023-10-16" @default.
• W2998989292 title "Pseudoxanthoma Elasticum: An Interesting Model to Evaluate Chronic Kidney Disease-Like Vascular Damage without Renal Disease" @default.
• W2998989292 cites W1897224010 @default.
• W2998989292 cites W193022306 @default.
• W2998989292 cites W1968143825 @default.
• W2998989292 cites W1982515902 @default.
• W2998989292 cites W1985914691 @default.
• W2998989292 cites W1989486548 @default.
• W2998989292 cites W2004583252 @default.
• W2998989292 cites W2017430811 @default.
• W2998989292 cites W2032287878 @default.
• W2998989292 cites W2046104930 @default.
• W2998989292 cites W2050322944 @default.
• W2998989292 cites W2059609157 @default.
• W2998989292 cites W2061046080 @default.
• W2998989292 cites W2062718484 @default.
• W2998989292 cites W2066291203 @default.
• W2998989292 cites W2066466374 @default.
• W2998989292 cites W2086031749 @default.
• W2998989292 cites W2091636827 @default.
• W2998989292 cites W2095804181 @default.
• W2998989292 cites W2105727026 @default.
• W2998989292 cites W2113854172 @default.
• W2998989292 cites W2116946904 @default.
• W2998989292 cites W2119823435 @default.
• W2998989292 cites W2131795083 @default.
• W2998989292 cites W2132586442 @default.
• W2998989292 cites W2134102591 @default.
• W2998989292 cites W2135064923 @default.
• W2998989292 cites W2140533230 @default.
• W2998989292 cites W2146662079 @default.
• W2998989292 cites W2147214514 @default.
• W2998989292 cites W2152995519 @default.
• W2998989292 cites W2623938296 @default.
• W2998989292 cites W2731826956 @default.
• W2998989292 cites W2734865411 @default.
• W2998989292 cites W2789793403 @default.
• W2998989292 cites W2790597051 @default.
• W2998989292 cites W2799394337 @default.
• W2998989292 cites W2804833119 @default.
• W2998989292 cites W285717869 @default.
• W2998989292 cites W2900301347 @default.
• W2998989292 cites W2900745773 @default.
• W2998989292 cites W2912201785 @default.
• W2998989292 cites W2963408498 @default.
• W2998989292 cites W4211002204 @default.
• W2998989292 cites W4230410214 @default.
• W2998989292 doi "https://doi.org/10.1159/000505026" @default.
• W2998989292 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7154277" @default.
• W2998989292 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32309291" @default.
• W2998989292 hasPublicationYear "2020" @default.
• W2998989292 type Work @default.
• W2998989292 sameAs 2998989292 @default.
• W2998989292 citedByCount "7" @default.
• W2998989292 countsByYear W29989892922020 @default.
• W2998989292 countsByYear W29989892922021 @default.
• W2998989292 countsByYear W29989892922022 @default.
• W2998989292 crossrefType "journal-article" @default.
• W2998989292 hasAuthorship W2998989292A5021622992 @default.
• W2998989292 hasAuthorship W2998989292A5061319183 @default.
• W2998989292 hasAuthorship W2998989292A5075780633 @default.
• W2998989292 hasAuthorship W2998989292A5087105111 @default.
• W2998989292 hasAuthorship W2998989292A5090919713 @default.
• W2998989292 hasBestOaLocation W29989892921 @default.
• W2998989292 hasConcept C126322002 @default.
• W2998989292 hasConcept C134018914 @default.
• W2998989292 hasConcept C142724271 @default.
• W2998989292 hasConcept C159641895 @default.
• W2998989292 hasConcept C164705383 @default.
• W2998989292 hasConcept C2776036575 @default.
• W2998989292 hasConcept C2776954043 @default.
• W2998989292 hasConcept C2777425297 @default.
• W2998989292 hasConcept C2778028898 @default.
• W2998989292 hasConcept C2778653478 @default.
• W2998989292 hasConcept C2779134260 @default.
• W2998989292 hasConcept C2780309369 @default.
• W2998989292 hasConcept C71924100 @default.
• W2998989292 hasConceptScore W2998989292C126322002 @default.
• W2998989292 hasConceptScore W2998989292C134018914 @default.
• W2998989292 hasConceptScore W2998989292C142724271 @default.
• W2998989292 hasConceptScore W2998989292C159641895 @default.
• W2998989292 hasConceptScore W2998989292C164705383 @default.
• W2998989292 hasConceptScore W2998989292C2776036575 @default.
• W2998989292 hasConceptScore W2998989292C2776954043 @default.
• W2998989292 hasConceptScore W2998989292C2777425297 @default.
• W2998989292 hasConceptScore W2998989292C2778028898 @default.
• W2998989292 hasConceptScore W2998989292C2778653478 @default.
• W2998989292 hasConceptScore W2998989292C2779134260 @default.
• W2998989292 hasConceptScore W2998989292C2780309369 @default.
• W2998989292 hasConceptScore W2998989292C71924100 @default.

• next