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• W2999045087 abstract "Adult undernutrition (BMI <18.5 kg/m2) is responsible for immune deficits, increased risk of disease burden, and higher rates of mortality. The prevalence of adult undernutrition in Bangladesh is substantial, but there have been few studies on the etiology of this condition for the inhabitants of urban slums.The aim of this study was to identify the factors associated with undernutrition among slum-dwelling adults in Bangladesh.A case-control study was conducted in the Bauniabadh area of Dhaka, Bangladesh. 270 adult participants (135 cases with a BMI <18.5 and 135 controls with a BMI between 18.5 and 24.9) aged 18-45 y were enrolled between October 2018 and January 2019. Sociodemographic variables, dietary diversity, micronutrient deficiencies, psychological symptoms, infection, and biomarkers of gut health were assessed to identify the factors associated with undernutrition using multivariable logistic regression analysis.A higher number of siblings [adjusted odds ratio (aOR): 1.39; 95% CI: 1.11, 1.77], increased self-reporting questionnaire-20 score (an instrument to screen mental health disorders and detect psychological symptoms) (aOR: 1.12; 95% CI: 1.04, 1.23), elevated fecal concentration of α-1 antitrypsin (aOR: 4.82; 95% CI: 1.01, 25.29), and anemia (aOR: 3.63; 95% CI: 1.62, 8.58) were positively associated with undernutrition in adults. Age (aOR: 0.90; 95% CI: 0.84, 0.96), dietary diversity score (aOR: 0.75; 95% CI: 0.56, 0.99), C-reactive protein (aOR: 0.82; 95% CI: 0.73, 0.92), Helicobacter pylori infection (aOR: 0.11; 95% CI: 0.05, 0.23), and always washing hands before eating or preparing foods (aOR: 0.33; 95% CI: 0.12, 0.87) were associated with reduced odds of undernutrition among the study population.Our results indicate that undernutrition in slum-dwelling adults in Bangladesh is associated with numerous physiological and sociodemographic factors, including evidence of gastrointestinal inflammation and altered intestinal permeability." @default.
• W2999045087 created "2020-01-23" @default.
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• W2999045087 date "2020-03-01" @default.
• W2999045087 modified "2023-09-30" @default.
• W2999045087 title "Evidence of gut enteropathy and factors associated with undernutrition among slum-dwelling adults in Bangladesh" @default.
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• W2999045087 doi "https://doi.org/10.1093/ajcn/nqz327" @default.
• W2999045087 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7049527" @default.
• W2999045087 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31909785" @default.
• W2999045087 hasPublicationYear "2020" @default.
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