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• W2999177497 abstract "Objectives Various modifiable and non-modifiable factors affect functional mobility, but subjective patient-reported and objective performance-based measures are rarely combined in explanatory analyses of functional mobility in people with limb loss. This study determined separate explanatory models for patient-reported function using the Prosthetic Evaluation Questionnaire Mobility Subscale (PEQ-MS), and performance-based 2-Minute Walk Test (2MWT). Design Retrospective cross-sectional observational analysis. Setting Wellness-walking program. Participants Three hundred five volunteers with lower limb loss participated. Sixty nine percent were men, mean age 56 (15) years. Fifty two percent had vascular amputation causes, 42% had surgical levels above the knee, and 82% had medical comorbidities. Walking levels included limited-household (21%), limited-community (30%), and independent-community (49%). Outcome measures included patient-reported PEQ-MS, Activities-specific Balance Confidence (ABC) and Houghton scales; and performance-based balance and walking. Main outcomes Separate PEQ-MS and 2MWT multiple regression models fit using backward deletion. Results Modifiable (balance ability, ABC, Houghton score; P < 0.05) and non-modifiable factors (sex, amputation cause, surgical level; P < 0.05) explained the variance in 2MWT (adjusted R2 = 0.685). Patient-reported and performance-based modifiable factors (Houghton score, 2MWT; P < 0.001) explained PEQ-MS variance (adjusted R2 = 0.660). Integumentary (P = 0.022) and cardiopulmonary (P < 0.001) comorbidities explained an additional 4% of PEQ-MS variance, while surgical level was insignificant. Conclusions Both modifiable and non-modifiable factors explained prosthetic functional mobility. Performance-based walking was explained by modifiable factors including balance ability and confidence, prosthesis and walking aid use. Patient-reported function was also explained by prosthesis and walking aid use, walking speed and medical comorbidities. Modifiable factors for objective and subjective prosthetic mobility may provide a clinical roadmap for rehabilitation." @default.
• W2999177497 created "2020-01-23" @default.
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• W2999177497 date "2020-06-01" @default.
• W2999177497 modified "2023-10-01" @default.
• W2999177497 title "Relevance of medical comorbidities for functional mobility in people with limb loss: retrospective explanatory models for a clinical walking measure and a patient-reported functional outcome" @default.
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• W2999177497 doi "https://doi.org/10.1016/j.physio.2020.01.002" @default.
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