FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2999278718> ?p ?o ?g. }

• W2999278718 endingPage "21" @default.
• W2999278718 startingPage "17" @default.
• W2999278718 abstract "Abstract Background: Lung tumours, especially those in the lower lobes, can move a lot during respiration; this motion needs to be accounted for during radiotherapy. In cases where 4D CT simulation scans are not performed, the current protocol at our centre is to apply a generic (internal motion + setup) margin of 0·70 cm in the axial plane and 1·20 cm in the longitudinal plane to all lung tumours, regardless of location. We analyse the tumour motions of a cohort of our local patients and categorise them into different locations in the lung. We seek to assess the adequacy of the current margins and to derive a more accurate set of standard margins which are specific for lung tumour locations. Methods: All cases of lung tumours treated with stereotactic ablative radiotherapy between 2012 and 2016 were identified retrospectively and 4D CT scan data analysed. These tumours were grouped into the following locations: upper zone (UZ), middle zone (MZ) and lower zone (LZ). The treatment planning system was used to generate the displacements of the centre of mass of the tumours in the right–left, anterior–posterior and superior–inferior axes; these were compared with the current generic margins. Median displacements were calculated for each axis in each location. New planning target volume (PTV) margins were derived by summing the median displacement, median absolute deviation (MAD) and 0·5 cm (for setup error). Results: Sixty-three cases were eligible for analyses. Motion in the superior–inferior direction was the greatest for all tumour locations, ranging from a median of 0·17 cm (MAD 0·12 cm) in UZ to 0·77 cm (MAD 0·27 cm) in LZ. Median tumour displacements in the anterior–posterior and right–left axes were similar for all locations, <0·30 and 0·20 cm, respectively. The current generic margins were adequate for only one-third of the cases in this study. A new PTV margin of 2·10 cm in the superior–inferior axis may be required for LZ tumours, while an additional 1–2 mm should be added to the current radial margins. Conclusion: The current generic margins are inadequate for the majority of cases. Tumour motion is the greatest in LZ in the superior–inferior axis. Motion mitigation strategies are essential for large LZ tumours." @default.
• W2999278718 created "2020-01-23" @default.
• W2999278718 creator A5003077306 @default.
• W2999278718 creator A5064626137 @default.
• W2999278718 date "2020-01-13" @default.
• W2999278718 modified "2023-09-23" @default.
• W2999278718 title "Correlating lung tumour location and motion with respiration using 4D CT scans" @default.
• W2999278718 cites W1972164006 @default.
• W2999278718 cites W2023670264 @default.
• W2999278718 cites W2037189699 @default.
• W2999278718 cites W2058185386 @default.
• W2999278718 cites W2070616815 @default.
• W2999278718 cites W2127480863 @default.
• W2999278718 cites W2149146010 @default.
• W2999278718 cites W2167767036 @default.
• W2999278718 cites W2472596403 @default.
• W2999278718 cites W2575050001 @default.
• W2999278718 cites W4232106085 @default.
• W2999278718 doi "https://doi.org/10.1017/s1460396919001043" @default.
• W2999278718 hasPublicationYear "2020" @default.
• W2999278718 type Work @default.
• W2999278718 sameAs 2999278718 @default.
• W2999278718 citedByCount "4" @default.
• W2999278718 countsByYear W29992787182021 @default.
• W2999278718 countsByYear W29992787182022 @default.
• W2999278718 countsByYear W29992787182023 @default.
• W2999278718 crossrefType "journal-article" @default.
• W2999278718 hasAuthorship W2999278718A5003077306 @default.
• W2999278718 hasAuthorship W2999278718A5064626137 @default.
• W2999278718 hasConcept C107551265 @default.
• W2999278718 hasConcept C119857082 @default.
• W2999278718 hasConcept C126322002 @default.
• W2999278718 hasConcept C126838900 @default.
• W2999278718 hasConcept C15744967 @default.
• W2999278718 hasConcept C201645570 @default.
• W2999278718 hasConcept C2777714996 @default.
• W2999278718 hasConcept C2989005 @default.
• W2999278718 hasConcept C41008148 @default.
• W2999278718 hasConcept C509974204 @default.
• W2999278718 hasConcept C542102704 @default.
• W2999278718 hasConcept C71924100 @default.
• W2999278718 hasConcept C774472 @default.
• W2999278718 hasConceptScore W2999278718C107551265 @default.
• W2999278718 hasConceptScore W2999278718C119857082 @default.
• W2999278718 hasConceptScore W2999278718C126322002 @default.
• W2999278718 hasConceptScore W2999278718C126838900 @default.
• W2999278718 hasConceptScore W2999278718C15744967 @default.
• W2999278718 hasConceptScore W2999278718C201645570 @default.
• W2999278718 hasConceptScore W2999278718C2777714996 @default.
• W2999278718 hasConceptScore W2999278718C2989005 @default.
• W2999278718 hasConceptScore W2999278718C41008148 @default.
• W2999278718 hasConceptScore W2999278718C509974204 @default.
• W2999278718 hasConceptScore W2999278718C542102704 @default.
• W2999278718 hasConceptScore W2999278718C71924100 @default.
• W2999278718 hasConceptScore W2999278718C774472 @default.
• W2999278718 hasIssue "1" @default.
• W2999278718 hasLocation W29992787181 @default.
• W2999278718 hasOpenAccess W2999278718 @default.
• W2999278718 hasPrimaryLocation W29992787181 @default.
• W2999278718 hasRelatedWork W1919433043 @default.
• W2999278718 hasRelatedWork W2047710313 @default.
• W2999278718 hasRelatedWork W2363834598 @default.
• W2999278718 hasRelatedWork W2513479736 @default.
• W2999278718 hasRelatedWork W2901599149 @default.
• W2999278718 hasRelatedWork W2980781247 @default.
• W2999278718 hasRelatedWork W3153034825 @default.
• W2999278718 hasRelatedWork W4237240905 @default.
• W2999278718 hasRelatedWork W4243045879 @default.
• W2999278718 hasRelatedWork W935391112 @default.
• W2999278718 hasVolume "20" @default.
• W2999278718 isParatext "false" @default.
• W2999278718 isRetracted "false" @default.
• W2999278718 magId "2999278718" @default.
• W2999278718 workType "article" @default.