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• W2999338963 abstract "Abstract The aim is to determine the prevalence of active infection by herpes simplex virus type 2 (HSV‐2) among Mexican women with high‐risk human papillomavirus (HR‐HPV) cervical infection, recruited from public gynecology and colposcopy services. In a cross‐sectional study, HSV‐2 antibodies, HSV‐2 DNA, and HR‐HPV DNA were quantified. Significant differences in HSV‐2 seroprevalence and HSV‐2 active infection rates were found between negative and positive HR‐HPV cases. HSV‐2 seroprevalence was 28.15% and 16.1% ( P = .0001), while HSV‐2 active infection rates were 6.83% and 0.62% ( P = .001) for positive and negative HR‐HPV groups, respectively. The risk of HSV‐2 seropositivity was 1.7 times greater for HR‐HPV‐positive cases ( P = .02). Similarly, HR‐HPV‐positive cases were nine times more likely to have an HSV‐2 active infection than HR‐HPV‐negative cases ( P = .03). High HSV‐2/h‐HPV coinfection rates were observed among women recruited from public gynecology and colposcopy services. The main factors related to an HSV‐2 active infection are a history of risky sexual behavior and HR‐HPV infection. The prevalence of HSV‐2 active infection among positive HR‐HPV subjects indicate that these infections constitute an important group of STIs in Mexico." @default.
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• W2999338963 date "2020-01-22" @default.
• W2999338963 modified "2023-10-06" @default.
• W2999338963 title "Prevalence of active infection by herpes simplex virus type 2 in patients with high‐risk human papillomavirus infection: A cross‐sectional study" @default.
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• W2999338963 doi "https://doi.org/10.1002/jmv.25668" @default.
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